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Although ethnic conflicts are an acute international problem, researchers in international relations have conducted surprisingly little research in this area. The aim with this study is to analyze one aspect of ethnic conflicts, how the elites representing ethnic groups act to make the great powers legitimize their own demands, and delegitimize the demands of the enemy by adducing to norms. In the
Acute myeloid leukemia (AML) remains the most common form of acute leukemia among adults and accounts for a large number of leukemia-related deaths. Mutations in FMS-like tyrosine kinase 3 (FLT3) is one of the most prevalent findings in this heterogeneous disease. The major types of mutations in FLT3 can be categorized as internal tandem duplications (ITD) and point mutations. Recent studies sugge
Serpentinite-hosted ecosystems are potential sites where life may first have evolved on Earth. Serpentinization reactions produce strongly reducing and highly alkaline fluids that are typified by high concentrations of molecular hydrogen (H2) and methane (CH4), which can be used as an energy source by chemosynthetic life. Low-temperature serpentinization at slow-spreading mid-ocean ridges provides
Lateralization is a fundamental property of the human brain that affects perceptual, motor, and cognitive processes. It is now acknowledged that left-right laterality is widespread across vertebrates and even some invertebrates such as fruit flies and bees. Honeybees, which learn to associate an odorant (the conditioned stimulus, CS) with sucrose solution (the unconditioned stimulus, US), recall t
BACKGROUND: Cancer of unknown primary (CUP) is a fatal cancer for which incidence trends have changed but detailed survival trends remain unexplored. These could point out successful diagnostic and therapeutic approaches. We investigate survival trends in CUP according to histology, locations of metastases and site-specific causes of death. PATIENTS AND METHODS: A total of 20,523 CUP patients with
A three-generation resource family was created by crossing two Berkshire grandsires with nine Yorkshire granddams to identify QTL affecting growth, body composition, and meat quality. A total of 512 F2 offspring were evaluated for 11 traits related to growth and body composition and 28 traits related to meat quality. All animals were initially genotyped for 125 markers across the genome. The objec
1. In adult decerebrate spinal rats whose plantar nerves (PLN) had been transected at either postnatal day 1. (P1) or P21 the nociceptive withdrawal reflexes (NWR) of musculi extensor digitorum longus (EDL), peroneus longus (PER) and semitendinosus (ST) were characterized with respect to receptive field (RF) organization, magnitude and time course, using electromyography. Thermal (short CO2 laser
Eight different generations of dolerite dykes crosscutting the Paleoproterozoic basement in West Africa and one in South America were dated using the high precision U–Pb TIMS method on baddeleyite. Some of the individual dykes reach over 300Â km in length and they are considered parts of much larger systems of mafic dyke swarms representing the plumbing systems for large igneous provinces (LIPs).
Sverige har både beskrivits som modernt, liberaldemoratiskt och djupt humanitärt; och som mer eller mindre förmodernt, halvauktoritärt och benäget att kränka svaga gruppers rättigheter. I den här avhandlingen undersöks detta svenska dilemma i en rättsantropologisk tradition, med studier av konfliktlösningspraktiker som ett sätt att förstå förhållandet mellan lag och kultur.Detaljerade data från tjSwedish society has been described as both modern, liberal democratic and deeply humanitarian; and as more or less premodern, semi-authoritarian and potentially abusive of groups with weak political representation. In this dissertation, this Swedish dilemma is explored in an anthropology of law tradition, with disputing practices as an inroad to an understanding of law as culture.Detailed data on
Objective: There is a paucity of sex-specific data on patients’ postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO). The present study sought to assess this issue in a multicenter study. Design: Retrospective, propensity score–matched analysis of an international registry. Setting: Multicenter study, tertiary university hospitals. Participants: Data on adult patients undergoi
BACKGROUND: Kwashiorkor, a form of severe malnutrition with high mortality, is characterized by edema and systemic abnormalities. Although extremely common, its pathophysiology remains poorly understood, and its characteristic physical signs are unexplained.OBJECTIVE: Because kwashiorkor can develop in protein-losing enteropathy, which is caused by a loss of enterocyte heparan sulfate proteoglycan
Background and Purpose: The EFFECTS (Efficacy of Fluoxetine - a Randomised Controlled Trial in Stroke) recently reported that 20 mg fluoxetine once daily for 6 months after acute stroke did not improve functional outcome but reduced depression and increased fractures and hyponatremia at 6 months. The purpose of this predefined secondary analysis was to identify if any effects of fluoxetine were ma
Adding metal-oxide shell layers is a promising route for improving the performance of metal nanoparticles (NPs) in various applications. However, despite the rapidly growing interest and a significant amount of experimental work on metal@metal-oxide NPs, computational modeling is relatively scarce, particularly on the sintering mechanism, which plays a crucial role in both the synthesis and perfor
Faryngotonsillit, eller halsfluss, är en vanlig orsak till att patienter söker primär-vård och är även en vanlig orsak till antibiotikaförskrivning. Bakterien Grupp A-streptokocker (GAS) har sedan länge varit den viktigaste mikroorganismen vid halsfluss, inte minst på grund av dess koppling till följdsjukdomar som exempelvis reumatisk hjärtsjukdom, men det finns många andra bakterier och virus somPharyngotonsillitis, or acute sore throat, is a common reason for attending primary health care and a common reason for antibiotic prescription. Group A Streptococcus (GAS) has long been considered the most important pathogen in pharyngotonsillitis, but a wide array of other bacteria and viruses have also been associated with this condition. However, few studies have used modern approaches for aet
The retinoblastoma gene product (pRb) is involved in both cell cycle regulation and cell differentiation. pRb may have dual functions during cell differentiation: partly by promoting a cell cycle brake at G(1) and also by interacting with tissue-specific transcription factors. We recently showed that pRb mediates differentiation of leukemic cell lines involving mechanisms other than the induction
Objectives To compare risks for COVID-19-related outcomes in inflammatory joint diseases (IJDs) and across disease-modifying antirheumatic drugs (DMARDs) during the first two waves of the pandemic and to assess effects of the pandemic on rheumatology care provision. Methods Through nationwide multiregister linkages and cohort study design, we defined IJD and DMARD use annually in 2015-2020. We ass
Background: Little is known about the effects of pesticides on children's respiratory and allergic outcomes.We evaluated associations of prenatal and current pesticide exposures with respiratory and allergic outcomes in children from the Infants' Environmental Health Study in Costa Rica.Methods: Among 5-year-old children (n=303), we measured prenatal and current specific gravity-corrected urinary
Contaminated drinking water (DW) is a major source of exposure to per- and polyfluoroalkyl substances (PFAS) at locations around PFAS production/use facilities and military airports. This study aimed to investigate quantitative relationships between concentrations in DW and serum of nine perfluoroalkyl acids (PFAAs) in Swedish adult populations living near contamination hotspots. Short-chained (PF
Objective: The aim of this study was to assess the cost effectiveness of oral semaglutide versus other oral glucose-lowering drugs for the management of type 2 diabetes (T2D) in Sweden. Methods: The Swedish Institute for Health Economics Diabetes Cohort Model was used to assess the cost effectiveness of oral semaglutide 14 mg versus empagliflozin 25 mg and oral semaglutide 14 mg versus sitagliptin
Based on the Baltic Earth Assessment Reports of this thematic issue in Earth System Dynamics and recent peer-reviewed literature, current knowledge of the effects of global warming on past and future changes in climate of the Baltic Sea region is summarised and assessed. The study is an update of the Second Assessment of Climate Change (BACC II) published in 2015 and focuses on the atmosphere, lan
