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Neurogenesis from Neural Stem Cells, Ependymal Cells and Fibroblasts

Popular Abstract in Swedish Stroke är en ledande orsak till dödlighet och handikapp i hela världen. Stroke leder till förlust av nervceller och även andra celler i hjärnan på grund av bristande blodtillförsel. För tillfället finns väldigt få möjligheter att behandla funktionshinder relaterade till stroke. Det har visats att stroke leder till ökad neurogenes, nybildning av nervceller i hjärnan. DenStroke is a major cause of death and disability around the world. Stroke leads to loss of neurons and also other cells in the brain due to lack of blood supply. Currently no therapies are available to treat stroke-related disability. It has been shown that stroke leads to increased neurogenesis, birth of new neurons, within the brain. This increased neurogenesis is not sufficient to restore lost f

Formgivning av motorkåpa

This thesis is the result of a work for Saab Automobile AB in Trollhättan, and more specifically the Department of under hood design. The project has been to Lund University and finishes my education in Technical Design. Supervisor at the company who has assisted me with much help is Andreas Barbunopulos and supervisors at the school have been Ola Carlquist and Karl-Axel Andersson. The purpose

Muntlig bevisning i hovrätten - en straffprocessuell studie ur ett nordiskt perspektiv

Muntlig bevisning har länge medfört problem i den svenska hovrätten. När ett mål når den andra instansen har kvaliteten på muntlig bevisning blivit sämre, inte minst på grund av att minnesbilder hos förhörspersoner försvagas med tiden. Trots det har utgångspunkten, allt sedan det muntliga och omedelbara förfarandet introducerades genom 1948 års rättegångsbalk (RB), varit att principen om det bästaOral evidence has caused problems in the Swedish courts of appeals for a long time. When a case reaches the higher court, the quality of oral evidence has deteriorated, primarily because the recollections of witnesses and parties have weakened over time. The starting point has, nevertheless, been that the principle of the best evidence requires renewed questioning of witnesses and parties in the c

Skenäktenskap i teori och praktik. Ett undantag från rätten till familjeåterförening

Sedan EU-direktivet om rätt till familjeåterförening införlivades i svensk rätt har makar rätt till familjeåterförening i Sverige. Denna rättighet är dock inte absolut, utan bortfaller om äktenskapet med lagtextens ord ingåtts uteslutande för att den ena maken ska få rätt till uppehållstillstånd (s.k. skenäktenskap). Till stöd för bedömningen av vad som är ett skenäktenskap finns kriterier i en EUSince the incorporation in Swedish law of the EU directive on family reunification, spouses have a right to family reunification. This right, however, is subject to limitations, e.g. for marriages which were contracted for the sole purpose of enabling the person concerned to obtain a residence permit (“marriages of convenience”). Criteria in aid of assessing which marriages are marriages of conven

Effects of gold- and silver nanoparticles on the retina

Att silver har en bakteriedödande effekt har varit känt sedan många århundraden. Historien om silver sträcker sig ända tillbaka till 4000 år före Kristus då de antika Kaldeérna använde silver och det var på den tiden en av mest använda metallerna tillsammans med guld och koppar. Persiska kungar föredrog att dricka vatten endast från bägare gjorda av silver för att vattnet kunde bevaras friskt och Over the past decade, a massive increase in the use of nanomaterials and nanoparticles (NPs) in both commercial and medical applications has occurred. Medical applications include advanced drug delivery vehicles, imaging and hyper thermic therapies. In retinal research, several nanomaterials have been explored in novel treatment approaches, ranging from metals, carbon, polymers and silica to biolo

Molecular Interrogation and Functional Studies of Acute Leukemia

Hematological malignancies are defined by their underlying genetic alterations, many of which are used to diagnose patients to classify them to different risk groups that dictate the therapy given. Recent advances in high-throughput sequencing have highlighted the presence of co-occurring genetic lesions and that they may form distinct genetic clones that evolve throughout disease progression. Acu

Female urinary incontinence. A study on heredity, urodynamic and hormonal factors and the evaluation of a novel surgical technique

Popular Abstract in Swedish Ofrivilligt urinläckage, urininkontinens, omfattar mer än 50 miljoner människor i världen, varav cirka 500 000 i Sverige. Av dessa beräknas 2/3 vara kvinnor. Ofrivilligt urinläckage är ett medicinskt och socialt handikapp för den drabbade, operation och hjälpmedel förorsakar samhället stora kostnader. Risken för urininkontinens ökar med stigande ålder. I svenska studierAbstract Pelvic floor disorders (PFD) represent a major public health issue worldwide. Aims of this work Study I: to investigate associations between preoperative resting urethral parameters (MUCP, FL and CA) and objective outcome of laparoscopic colposuspension and, if possible, to identify cutoff values useful in clinical practice. Study II: to investigate a group of perimenopausal women reporti

Early Palaeozoic jawed polychaetes with focus on polychaetaspids and ramphoprionids from the Silurian of Gotland, Sweden

Popular Abstract in Swedish Käkförsedda havsborstmaskar (polychaeter) var artrika och vanliga i de tidigpaleozoiska haven. Maskarnas käkar, benämda scolecodonter i den vetenskapliga litteraturen, är mycket vanliga mikrofossil i sedimentära bergarter, främst kalkstenar av denna ålder. Mycket pekar därför på att de ofta utgjorde en väsentlig del av bottenfaunan. Trots mångfalden av scolecodonter harJawed polychaete annelid worms were abundant and diverse in the early Palaeozoic seas and their jaws (scolecodonts) are common microfossils in sedimentary rocks of that age. Despite their abundance, relatively little work has been focused on these fossils. One reason for this is that their taxonomy has been, and to some extent still is, in a state of disorder, mainly because of a parataxonomic tre

Laminar-flow Liquid-to-air Heat Exchangers - Energy-efficient Display Cabinet Applications

Popular Abstract in Swedish Resultaten som presenteras i denna doktorsavhandling visar att det går att spara stora mängder energi genom att använda samma typ av värmeväxlare, som normalt används i bilar och lastbilar, i livsmedelsbutikernas kyldiskar. För att hålla maten kall när den ligger ute i butiken cirkuleras en kyld luftström runt i kyldiskarna. Denna kyls i en så kallad värmeväxlare som Provisions are stored and displayed in supermarkets and grocery stores, at a temperature lower than the ambient, in display cabinets, which are responsible for a significant amount of the energy use in this sector. During the 1990s, major changes in the regulations governing the use of synthetic refrigerants took place in Sweden. This resulted in many refrigeration systems being converted to syste

Systematic trend of water vapour absorption in red giant atmospheres revealed by high resolution TEXES 12 mu m spectra

Context. The structures of the outer atmospheres of red giants are very complex. Recent interpretations of a range of different observations have led to contradictory views of these regions. It is clear, however, that classical model photospheres are inadequate to describe the nature of the outer atmospheres. The notion of large optically thick molecular spheres around the stars (MOLspheres) has b

The Columnar Lined Esophagus. Pathophysiological and Clinical Aspects

Popular Abstract in Swedish Gastroesofageal refluxsjukdom är ett tillstånd som kännetecknas av att magsyra åker upp i matstrupen (reflux). Reflux är ett normalt fenomen som förekommer hos alla individer utan att orsaka symtom eller vävnadsskador. Hur detta normaltillstånd utvecklas till ett sjukdomstillstånd är ej helt klarlagt. Reflux förhindras normalt av en barriär vid övergången mellan matstruThere is a persisting controversy concerning the definition, etiology and pathogenesis of Barrett's esophagus. The dramatic and parallel increase in the incidence of esophageal and junctional adenocarcinoma over the past decades justifies an evaluation of the pathophysiology of premalignant metaplastic changes of the esophagus and the gastroesophageal junction. Patients were evaluated with upper G

Adaptive flexibility in migratory behaviour of shorebirds

Popular Abstract in Swedish I århundranden har vi människor fascinerats av flyttfåglar och frågat oss vart de ska, var de kommer ifrån och hur de hittar. Idag, tack vare forskning, vet vi mer om fågelflyttning än någonsin, men det finns fortfarande mycket kvar att ta reda på. Vadare som häckar i Arktis är riktiga långflyttare med många arter som flyttar mer än 10 000 kilometer varje vår och höst oThe phenomenon of bird migration has long fascinated us humans and it has prompted questions like where do they go or come from and how do they find their way? Arctic shorebirds are well known for their spectacular long-distance migrations with some species travelling more than 10 000 km every spring and autumn, and some even cover this distance in one single nonstop flight. The aim of my thesis w

Microbial Degradation of Toxaphene

This works deals with the degradation of a group of recalcitrant compounds known as toxaphene. Toxaphene is a complex mixture of chlorinated compounds including hexa- and octachlorocamphenes, hepta-, nona- and decachlorobornanes. Some components of toxaphene are very persistent while others are degraded rapidly by both abiotic and biotic processes. Not all components of toxaphene have been identif

The Ups and Downs of the Holocene: Exploring Relationships between Global CO2 and Climate Variability in the North Atlantic Region

This thesis aimed to examine the relationship between climate and atmospheric CO2 concentrations through rapid climate changes during the Holocene. Climate was reconstructed using high-resolution, radiocarbon dated, lake sediment geochemical proxies (magnetic susceptibility, loss-on-ignition, total carbon/nitrogen/sulphur determinations and biogenic silica), vegetational reconstruction (pollen ana

Parents' travel mode choice for their children's leisure journeys - role of trust.

Many parents perceive the urban environment as hazardous for their children and therefore prescribe and circumscribe young people’s access to the environment (Malone, 2001). Consequently, spontaneous unregulated play in neighbourhood spaces is decreasing as children are primarily encouraged to participate in regulated play environments in their homes, friends houses and commercial facilities. Simu

Identification of principal chemical subsets of biofuel combustion : Ants walking in renewable fire

The work in this thesis was carried out to highlight important chemical pathways in skeletal mechanisms for the three smallest alcohol fuels (methanol, ethanol and npropanol), two representative fuel alkanes n-heptane and n-decane, and finally the biodiesel surrogates, methyl-decanoate, methyl-5-decenoate, and methyl-9-decenoate. This aim was set up to further the efforts of creating Computational

Seasonality of the particle number concentration and size distribution: A global analysis retrieved from the network of Global Atmosphere Watch (GAW) near-surface observatories

Aerosol particles are a complex component of the atmospheric system which influence climate directly by interacting with solar radiation, and indirectly by contributing to cloud formation. The variety of their sources, as well as the multiple transformations they may undergo during their transport (including wet and dry deposition), result in significant spatial and temporal variability of their p

Droplet, aerosol and SARS-CoV-2 emissions during singing and talking

IntroductionAs the pandemic continues to spread, more knowledge is needed about the viral transmission routes. Several super spreading events during the Covid-19 pandemic have been linked to singing in choirs and talking loud. However, in the beginning of the pandemic there was only one study about emitted aerosols and droplets from singing, published in 1968, and only a handful on emissions from

Hur kan kontor bli hem? - Konvertering av kontorslokaler till bostäder ur ett fastighetsägarperspektiv

De svenska kontorsmarknaderna i Stockholm, Göteborg och Malmö har sett ökade vakansgrader under de senaste åren. En viktig faktor bakom detta är anställdas preferenser efter Covid-19-pandemin. Även om närvaron på kontoren har börjat öka igen, har utnyttjandegraden sjunkit i Sverige, och hyresgäster prioriterar nu sin hyresportfölj och ytoptimering för att spara kostnader. Vakans i kontorsbyggnaderThe Swedish office markets especially in the three major cities Stockholm, Gothenburg, and Malmö have experienced increased vacancy rates in recent years. One key factor behind this is employees' preferences post the Covid-19 pandemic. Despite a gradual return to offices, the utilization rate has decreased in Sweden, prompting tenants to prioritize their lease portfolios and space optimization

In vivo knee cartilage quality assessment by direct quantification of glycosaminoglycans through chemical exchange saturation transfer (gagCEST)

Introduction: Non-invasive imaging of human articular cartilage is an important tool in understanding, and thus allowing the development of effective treatments for, osteoarthritis; a disease responsible of impaired movement of millions of otherwise healthy individuals. Glycosaminoglycans (GAG) have been attributed with important biomechanical properties, vital for the function of the articular ca