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Immunoglobulin-binding bacterial surface proteins; biomedical tools and virulence factors
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Antikroppar, även kallade immunoglobuliner, är proteiner som utgör en viktig del i vårt försvar mot infektioner genom att de kan binda och neutralisera ämnen som uppfattas som främmande, t ex bakterier, virus eller produkter som produceras av dessa organismer. Antikropparna består av en antigen-bindande variabel del som binder till deMany bacteria express immunoglobulin(Ig)-binding proteins that interact with Ig in a non-immune manner. Several of these Ig-binding bacterial proteins have been well characterized and are widely used as reagents for analysis and purification of Ig's. Protein G found on group C and G streptococci has affinity for constant regions of IgG heavy chains, whereas protein L found on Peptostreptococcus ma
Rött kort för sportswashing: En kvalitativ analys av Saudiarabiens nationsvarumärkning
Denna kandidatuppsats är en kvalitativ undersökning över hur länder i en rykteskris använder nationsvarumärkning och mjuk makt för att motverka negativa stereoty- per och förbättra sitt globala rykte. Nationsvarumärkning beskrivs som ett strate- giskt verktyg för att förbättra ett lands rykte och attraktivitet genom olika mark- nadsförings- och varumärkesmetoder. Flerstegsmodellen introduceras som
30th Anniversary: Seminar, Reading Hannah Arendt: On Art – its political importance for judging between right and wrong
20 november 2025 13:00 till 16:00 | Seminarium Due to the high interest in this seminar, we have decided to take pre-registrations. Register by sending an e-mail to khm [at] khm [dot] lu [dot] se (khm[at]khm[dot]lu[dot]se)____________________Reading Hannah Arendt: On Art – its political importance for judging between right and wrongHannah Arendt is primarily a political thinker, but her view of t
γ-globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response
It has previously been shown that sera from multiparous women have increased levels of anti-idiotypic antibodies specific for anti-HLA molecules. γ-Globulins prepared from these sera may be superior to commercial preparations of intravenous γ-globulin (IVIg) for inhibiting HLA alloimmunization. To test this, F(ab′)2 fragments prepared from either commercial IVIg or from the sera of men or multipar
Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy
Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,
The impact of green roofs on the urban heat island effect : a study on Augustenborg, Malmö
With the growth of cities more issues relating to the environment, economy and health have emerged. The climate in the city affects how the city is structured and how the city space is used. In return the city also has an effect on the climate by modifying the regional climate conditions on a large scale. This has led to an increase in air temperature in the urban areas causing an urban heat islanGrowth of cities has caused the climate in them to change making urban areas warmer than the surrounding rural areas. This phenomenon is called an urban heat island. Mitigation tactics to counter the heating of the urban areas vary from changing the thermal properties of the surface materials to adding vegetation and water bodies to the urban scene. This study aims to investigate the impact green
Coordination Complexes of Molybdenum with 3,6-Di-tert-butylcatechol. Addition Products of DMSO, Pyridine N-oxide, and Triphenylarsine Oxide to the Putative [MoVIO(3,6-DBCat)2] Monomer and Self-Assembly of the Chiral [{MoVIO(3,6-DBCat)2}4] Square
Molybdenum complexes of 3,6-di-tert-butylcatechol have been prepared from the reaction between [Mo(CO)6] and 3,6-di-tert-butyl-1,2-benzoquinone. A putative "[MoO(3,6-DBCat)2]" monomer is assumed to form initially by reaction with trace quantities of oxygen. Condensation of the reaction mixture leads to the formation of oligomeric products, including the [{MoO(3,6-DBCat)2}4] chiral square isolated
Vulnerability versus resilience to prenatal stress in male and female rats; Implications from gene expression profiles in the hippocampus and frontal cortex
Adverse life events during pregnancy may impact upon the developing fetus, predisposing prenatally stressed offspring to the development of psychopathology. In the present study, we examined the effects of prenatal restraint stress (PS) on anxiety- and depression-related behavior in both male and female adult Sprague-Dawley rats. In addition, gene expression profiles within the hippocampus and fro
Germline heterozygous variants in genes associated with familial hemophagocytic lymphohistiocytosis as a cause of increased bleeding
Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3–5, the affected genes UNC13D, STX11 and STXBP2 have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients heterozygou
Human IgG/FcgammaR Interactions Are Modulated by Streptococcal IgG Glycan Hydrolysis.
Enhancement Requests 2023
Phase 1/2a clinical trial of BI-1206, an anti-CD32b (FcγRIIB) antibody, in combination with pembrolizumab in subjects with advanced solid tumors previously treated with anti-PD-1/PD-L1.
2593Background: PD-1 blockade has demonstrated positive anti-tumor activity across multiple tumor types. While the anti-tumoral response can be substantial and even curative, response rates remain low in many cancer types. Long-lasting responses are only observed in a minority of patients, and additional immunotherapeutic alternatives remain limited for patients who fail to respond or initially re
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Firefighter fatalities in Sweden, 1937 - 2016
The purpose of this work was to present collective data on firefighter fatalities in Sweden between 1937 and 2016. Data presented is directly related to operations only. Fatalities due to long-term exposure of gases, particles, and physical/psychological stress or similar were not included in the study. Also, accidents involving ambulances as well as fatalities in direct relation to physical train
Ett rationellt samhälle för alla
This essay deals with the concept of rationality. More precisely how rationality is defined within the thoughts of the philosopher Jürgen Habermas and what consequenses this may have for different views of life. By analyzing Habermas thoughts with the experiences obtained from a presumptionistic perspective the study takes form as a critical evaluation of Habermas outspoken pluralistic and accep
The Migration Industry and the Commercialization of International Migration - The Raoul Wallenberg I
The Migration Industry and the Commercialization of International Migration - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice
https://rwi.lu.se/publications/the-migration-industry-and-the-commercialization-of-international-migration/ - 2026-05-05
Sommar-kickoff
17 juni 2026 16:00 | Gemensamma aktiviteter Onsdag den 17 juni kl 16 ses vi för att önska varandra en skön sommar och god läslust i hängmattan. Vi kör nämligen en favorit i repris: Bokbytarbord! Ta med en (skönlitterär) bok du läst som du kan rekommendera, och byt med kollegerna.Vi skålar i bubbel och mumsar på tårta och jordgubbar. Om vädret tillåter är vi ute bakom SamBib, annars inne i vår foaj
https://www.soch.lu.se/internt/evenemang/sommar-kickoff-0 - 2026-05-05
