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Planets that orbit their host star closely experience tidal forces due to the strength of gravity not being uniform all over the planet. This leads to effects such as tidal spin synchronization, tidal eccentricity damping and tidal semi-major axis damping. This project aims to study how the time scales for these phenomena are affected by the planetary parameters such as mass, radius and the tidal
We report the development of a high-level bacterial expression system for the Alzheimer's disease-associated amyloid beta-peptide (A beta), together with a scaleable and inexpensive purification procedure. A beta(1-40) and A beta(1-42) coding sequences together with added ATG codons were cloned directly into a Pet vector to facilitate production of Met-A beta(1-40) and Met-A beta(1-42), referred t
Epigenetic code modifications by histone deacetylase inhibitors (HDACis) have recently been proposed as potential new therapies for hematological malignancies. Diffuse large B-cell lymphoma (DLBCL) is the most common form of aggressive lymphoma. At present, standard first line treatment for DLBCL patients is the antracycline-based chemotherapy regimen CHOP (cyclophosphamide, doxorubicin, vincristi
X-ray and neutron reflection studies, the latter in conjunction with contrast variation, have been combined to study the interaction of calf thymus DNA (ctDNA) with monolayers of distearoylphosphatidylcholine (DSPC) in the presence of 20 mM Ca2+ ions, at the air–liquid interface as a function of surface pressure (10, 20, 30 and 40 mN m−1). Analysis of the X-ray and neutron reflection data showed t
A spectrophotometric assay for plasmin and plasminogen-derived activity in dairy products was optimised and extended to determine plasmin and plasminogen-derived activity in turbid samples of dairy products. The method was validated by assessing reproducibility, repeatability, level of detection and recovery of plasmin activity in different sample matrices. Plasmin activity in raw milk was not aff
In this study, two experiments were conducted to evaluate the impact of substrate concentrations on methane potential and degradation kinetics of substrate. The biochemical methane potential (BMP) tests in Experiment I were performed at a constant inoculum to substrate ratio (ISR), whereas, different ISRs were applied in Experiment II. Results obtained from Experiment I revealed that methane poten
To catalyse transition toward a more sustainable economy, the European Union is proposing several policy interventions within the regulatory framework governing the financial sector. As part of this effort, a new EU Eco-label policy for green investment funds seeks to (i) facilitate individual investor participation in the sustainable investment market and (ii) increase private sector investments
In the field of molecular biology, the cloning of DNA is a vital process. Through cloning, researchers can design new DNA strands which can be used for a number of applications. One of these applications is the creation of synthetic antibodies for cancer treatments. Alligator Bioscience is developing a high-throughput chain to significantly speed up the process. Traditional cloning techniques rely
Professional counselors are often seen as responsible for highlighting the need of, and to operate the social work in healthcare. To have that expertise in an otherwise medical context can lead to it being a difficult task. It is also suggested that the social worker’s role and professional identity is vague, which also influences social worker’s jurisdictional work. The aim of this study was to i
High-rise buildings are exposed to both static and dynamic loads. Depending on the method used and how the structure is modelled in finite element software the results can vary. Some of the issues and modelling techniques, introduced below, are investigated in this Master’s thesis. Dynamic effects such as resonance frequencies and accelerations are considered. The variation in static results from
The thiol-disulfide oxidoreductase ResA from Bacillus subtilis fulfils a reductive role in cytochrome c maturation. The pK(a) values for the CEPC (one-letter code) active-site cysteine residues of Ill are unusual for thioredoxin-like proteins ill that they are both high (> 8) and within 0.5 unit of each other. To determine the contribution of the inter-cysteine dipeptide of ResA to its redox and a
This study addresses gender assignment in six North Scandinavian varieties with a three-gender system: Old Norse, Norwegian (Nynorsk), Old Swedish, Nysvenska, Jamtlandic, and Elfdalian. Focusing on gender variation and change, we investigate the role of various factors in gender change. Using the contemporary Swedish varieties Jamtlandic and Elfdalian as a basis, we compare gender assignment in ot
Disentangling the individual and interactive effects of multiple stressors on microbial communities is a key challenge to our understanding and management of ecosystems. Advances in molecular techniques allow studying microbial communities in situ and with high taxonomic resolution. However, the taxonomic level which provides the best trade-off between our ability to detect multiple-stressor effec
Purpose To study the epidemiology of Dupuytren disease and evaluate treatment outcome of collagenase injections using a modified method.Patients and methods Paper I is a register-based study. From the general population of Skåne region (1.3 million) in southern Sweden, we identified all residents aged ≥20 years who had been diagnosed with Dupuytren disease during a 16-year period and identified tr
The purpose of this investigation is to explore and highlight the role of the Third World within a human rights framework during the era of decolonization. More specifically the investigation analyzes in what ways states from the Third World used human rights to argue for the abolishment of colonialism within the context of debates in the 15th session of the UN General Assembly in 1960 and in rela
Sweden has in the past decade embarked on a journey to rebuild the concept of ‘total defence’. The crisis management system led by the Swedish Civil Contingency Agency has become all-the-more involved in the civil defense, with the Swedish Armed Forces responsible for military defense. The present thesis aims to explore the topic of gender and language in Sweden’s total defense discourse to uncove
Purpose: The purpose of this paper is to investigate whether firms react to covenant pressure pre-breach event by adjusting their operational and financial strategies. Methodology: The econometric approach of choice is a firm fixed effects panel regression on the sample of firm-year observations. The regressions use a treated form of interest coverage slack as the main explanatory variable, while
This study presents the analysis of Upper Triassic sediments from five locations in North Dobrogea (Romania) and the Black Sea. Microfacies analyses on thin sections from the Frecăţei log reveal a shallowing trend and likely an increase in energy upward into the section. The oldest part of the log is characterised by deposition of mudstones transitioning to wackestones, wit
Modern subgraph-finding algorithm implementations consist of thousands of lines of highly optimized code, and this complexity raises questions about their trustworthiness. Recently, some state-of-the-art subgraph solvers have been enhanced to output machine-verifiable proofs that their results are correct. While this significantly improves reliability, it is not a fully satisfactory solution, sinc
