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Mycobacterium marinum promotes mitochondrial degradation in an ESX-1 dependent manner

Investigating the role of mitochondrial damage in a Tuberculosis infection Tuberculosis (TB) is a significant health risk that was responsible for 10.4 million infections and 1.8 million deaths in the year 2015 alone. The causative agent for TB is Mycobacterium tuberculosis (Mtb), which is an intra-cellular bacterium that primarily replicates within the white blood cell called the macrophage. To

Multidimensionality of Socioeconomic Status and its Effect on Health Outcomes in Contemporary Estonia

Socioeconomic status (SES) and its effect on health outcomes for an individual is generally well researched, but the different mechanisms of different socioeconomic factors are yet still not fully understood. Using cross-sectional survey data for 50+ people in Estonia this thesis aims to analyse the multidimensional nature of different SES variables to see if the SES variables have an independent

Artificial Neural Network Modelling of Intensive Care Mortality

In order to study and evaluate the care provided at the Intensive Care Unit (ICU), an accurate model to assess severity of illness and predict patient mortality based on admission data is required. Since 1983, the Simplified Acute Physiology Score (SAPS) based on logistic regression (LR) has become one of the international standards for this purpose and is used in Sweden for adults. While being a

"Man har alltid en smekmånad när barnet kommer, men där finns ju alltid problematik, det är ju därför man får ett barn"

Research suggest that foster children’s school achievements in compulsory school are worse compared with their peers in the same age group. The purpose of my study was to explore and analyze what kind of support and assistance foster children are offered in order to leave the compulsory school with approved grades. Furthermore, the aim was also to explore what kind of sup¬port that the social serv

A Comprehension of Spinoza's God: Through the Dichotomy of Labels

Abstract: The 17th century philosopher Spinoza is known for his concept of God as One Substance, God or Nature and therefore considered as a monist and categorized as a naturalist. He has been labeled an atheist and God-intoxicated man, as well as a determinist and pantheist, which I perceive to be dichotomies. The problem, as I see it, is that Spinoza’s philosophy and concept of God has mainly be

Maternal Education and Preventive Behaviour - Evidence from Zimbabwe´s Educational Reform

This paper aims to investigate the causal relationship between maternal education and preventive behaviour. For this purpose, I consider the education reform implemented in Zimbabwe in 1980 that enabled students at age 15 and below to participate in secondary education. By using this age cutoff as an exogenous exposure to the education policy, I obtain causal estimates of schooling on health outco

Mitt, ditt eller vårt – vad gäller och vilket skydd ger lagen en efterlevande sambo?

SAMMANFATTNING En allt större andel av befolkningen sammanlever som sambor. Sambolagen (2003:376) reglerar fördelning av det gemensamma hemmet vid samboförhållandets upplösning, med huvudsyftet att erbjuda ett minimiskydd för den svagare parten. Det finns stora skillnader i det lagreglerade skyddet för en efterlevande make och en efterlevande sambo. En skillnad ligger i att makar, men inte samborSUMMARY The number of the population living as cohabitees is steadily increasing. The Cohabitees Act (2003:376) regulates the division of the mutual household in the event of the cohabitees resolvement, with the main purpose to offer a minimum protection for the weaker party. There are multiple differences in the regulating law for a surviving spouse and cohabitee. One of the differences is that s

Moisture Conditions and Frost Resistance of Concrete in Hydraulic Structures

Med avseende på de svenska förhållandena vintertid kan frostpåverkan antas ha betydande inverkan på nedbrytningen av betong i vattenbyggnader. Både ytliga och inre skador, vilka misstänks ha orsakats av frostpåverkan, har upptäckts på betong i exempelvis vattenkraftkonstruktioner. Nämnda observationer har väckt frågor om vattenbyggnaders beständighet i ett kallt klimat. Ytligt belägna skador, vilOwing to the winter conditions in Sweden, the effects of frost action may have a considerable impact on the deterioration of concrete. Both superficial and internal damage, which are suspected to have been caused by frost action, have been found in concrete in hydraulic structures. These observations have raised questions about the long-term behaviour of hydraulic structures in cold regions. Supe

Effect on Survival and Hospitalization of Initiating Treatment for Chronic Heart Failure With Bisoprolol Followed by Enalapril, as Compared With the Opposite Sequence. Results of the Randomized Cardiac Insufficiency Bisoprolol Study (CIBIS) III.

Background - In patients with chronic heart failure (CHF), a beta-blocker is generally added to a regimen containing an angiotensin-converting-enzyme ( ACE) inhibitor. It is unknown whether beta-blockade as initial therapy may be as useful. Methods and Results - We randomized 1010 patients with mild to moderate CHF and left ventricular ejection fraction <= 35%, who were not receiving ACE inhibitor

Mapping Potential Distribution for the Endangered Wild Asses of Asia, Equus hemionus

Popular science summary: Potential Distribution for the Endangered Asian Wild Ass Over the past century, large mammals have been globally under increasing pressure of humanized landscapes. Since extirpations of large herbivores are likely to have complicated consequences for the entire ecosystem, their conservation is a priority. With almost 81% threatened species, Perissodactyla (odd-toad ungu

Privatization of elderly care in Sweden: a comparison between quality of public and private home care services

The privatization of elderly care system occurred in response to an economical crisis as well as political decisions made in the early 1990‘s. Since the economic crisis was supposed to have a negative impact on quality of elderly care services, the government adopted different policies such as New Public Management strategies, the introduction of a unit price for all care services, and the law imp

Privatization of elderly care in Sweden: a comparison between quality of public and private home care services

The privatization of elderly care system occurred in response to an economical crisis as well as political decisions made in the early 1990‘s. Since the economic crisis was supposed to have a negative impact on quality of elderly care services, the government adopted different policies such as New Public Management strategies, the introduction of a unit price for all care services, and the law imp

Försäljningskanalstrategi - En kartläggning av försäljningskanaler inom verkstadsindustrin

The Master Thesis investigates the way Sandvik Coromant use its sales channels and how they can utilize them in a more effective way. This Master Thesis has been written at Coromant Business in Sandviken during spring and summer 2002. Sandvik Coromant has gone from being a product-oriented company to being more customers oriented, which means that you have to understand the market, the customers a

Enhancing Phycotoxin Forecasting: The Role of Zooplankton Monitoring in Harmful Algal Bloom Management

Harmful algal blooms pose a threat to public health and the economy, affecting tourism, fisheries, and aquaculture. Complex environmental factors influence their occurrence, but current forecasting models often overlook the role of grazers. Chemical cues released by zooplankton, copepodamides, can trigger the production of toxins in harmful algae. Therefore, their presence in bivalves may enhance

Coexistence of Dual Inductive Wireless Power Transfer Systems

Wireless power transfer is emerging into everyday life. The idea is to create a more convenient way of charging, or at least powering, devices. Ideally, all power transmitters and power-receiving devices should be interoperable so that the user does not need to investigate whether a specific power transmitter will work together with a specific device. Interoperability is what the standard Qi, inve

Omskärelse av pojkar - en argumentationsanalys av den svenska debatten

In Swedish law boys under the age of 18 can legally be circumcised by a certified doctor or a person with a special permission from the welfare board. This is a measure to prevent ignorant people from performing circumcision on boys in unsterile environment and without painkillers. The law has brought up a debate questioning if circumcision should be legal at all in Sweden. The network SNOP – Säg

Inadequate educational attainments: A study of boys in a small fishing village in Iceland

In this thesis I have presented possible indicators affecting boys’ educational attainments and learning behaviors. In my study I used both quantitative and qualitative methods. First, I studied the relationship between knowledge of relational concepts and later academic achievements. The data consisted of two different types of tests (Boehm Test of Basic Concepts and National Standard Tests). The

Geografiska skillnader vid användning av restriktioner och en analys av dess orsaker

En medborgare är gentemot det allmänna skyddad mot frihetsberövande enligt svensk grundlag. Det finns dock undantag från denna grundlagsskyddade rättighet om begränsningen sker genom lag och tillgodoser ändamål som är godtagbara i ett demokratiskt samhälle. Det får aldrig gå utöver vad som är nödvändigt med hänsyn till det ändamål som har föranlett begränsningen. Något som är reglerat i lag och A citizen is against the public protected from detention by the Swedish Constitution. There are exceptions to this fundamental right if the restriction is done by law and meets the purposes that are acceptable in a democratic society. It must never go beyond what is necessary with regard to the purpose which caused the restriction. Something that is regulated by law and is considered acceptable

The effect of brood size on the development of homeothermy in blue tit (Cyanistes caeruleus) nestlings

Populärvetenskaplig sammanfattning: Kullstorlek och förmågan att hålla värme Direkt efter kläckning har de flesta fågelungar svårt att hålla en jämn kroppstemperatur (termoreglera) i en kallare omgivning. Förmågan att termoreglera uppkommer eller utvecklas någon gång under ungarnas första tid i livet och snart är de mer eller mindre jämnvarma. Förmågan att hålla en jämn kroppstemperatur tidigt iAbstract Most birds are not capable of maintaining core body temperature when exposed to cold ambient temperatures directly after hatching. As postnatal development continues the thermoregulatory capacity begins to form, and eventually nestlings become homeothermic. Many factors, such as predation, latitude and foraging mode, may influence this development of homeothermy, but to my knowledge no s