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Bleeding peptic ulcer - time trends in incidence, treatment and mortality in Sweden.

Abstract Background: The incidence of peptic ulcer disease was expected to decrease following the introduction of acid inhibitors and H. pylori eradication. Aim: This study analyses possible changes in the incidence of bleeding peptic ulcer, treatment and mortality over time. Methods: Residents of Malmö hospitalised for bleeding gastric or duodenal ulcer disease1987-2004 were identified in hospita

Early menopause is an independent predictor of rheumatoid arthritis.

BACKGROUND: As rheumatoid arthritis (RA) occurs more often in women than in men, it has been suggested that reproductive hormones may play an important role in the pathogenesis.METHODS: Between 1991 and 1996, 30 447 subjects (18 326 women) were included in a community-based health survey. Information on female hormonal changes and stress-related factors was obtained using a self-administered quest

Numerical evaluation of different landfill daily cover in semiarid areas – Jordan

Efficient and suitable daily landfill cover is considered the most important aspect for minimising the negative impact of landfills on the local environment and population, especially in arid and semiarid countries. In this study, numerical model, HYDRUS-2D/3D, was used to investigate the impact of landfill cover type, cover thickness and antecedent water content on the quantity and the rate of co

Prestudy on diffusion and transient condensation of water vapor in cement mortar

The kinetics of sorption of water vapor in mature cement mortar are examined experimentally by the use of a sorption balance (DVS1000). The relative humidity in the sample chamber is obtained by mixing dry and saturated air using flow regulators with very high accuracy. A predefined change of relative humidity in the sample chamber can be obtained in about 30 s. The time needed for equilibration i

The incidence of intrinsic and extrinsic ligament injuries in scaphoid waist fractures.

PURPOSE: To determine the incidence of associated intrinsic and extrinsic ligament injuries in patients with a nondisplaced or displaced scaphoid waist fracture. METHODS: During a 3-year period, a study of all scaphoid fractures was performed at our institution. Diagnosis was confirmed by plain radiographs, computed tomography, and magnetic resonance imaging. A 3-part anatomic classification was u

Challenge-induced plasma exudation and mucinous secretion in human airways

Secretion of mucins and exudation of plasma are distinct processes of importance to innate immunity and inflammatory disease. Yet, little is known about their relation in human airways. The objective of the present study was to use the human nasal airway to determine mucinous secretion and plasma exudation in response to common challenge agents and mediators. Ten healthy volunteers were subjected

Outcome of the Swedish Nationwide abdominal aortic aneurysm screening program

Background: A general abdominal aortic aneurysm (AAA) screening program, targeting 65-year-old men, has gradually been introduced in Sweden since 2006 and reached nationwide coverage in 2015. The aim of this study was to determine the outcome of this program. Methods: Data on the number of invited and examined men, screening-detected AAAs, AAAs operated on, and surgical outcome were retrieved from

Multi-parametric flow cytometric cell cycle analysis using TO-PRO-3 iodide (TP3) : detailed protocols

TO-PRO-3 iodide (TP3), a monomeric cyanine nucleic acid stain with a peak absorbance at 642 nm and emission at 661 nm, is best excited by a helium-neon (HeNe) laser (633nm). It was tested in monocytes and different cell lines under conditions of different fixatives, dye concentrations, labeling kinetics and RNAse concentrations for mono-, bi- and tri-parametric flow cytometric cell cycle analysis

Cytogenetic studies of normal kidney tissue and renal cell carcinoma

Popular Abstract in Swedish Njurcancer är ungefär den 10:e vanligaste tumörformen i Sverige och diagnosticeras nästan dubbelt så ofta hos män som hos kvinnor. Tumörerna upptäcks vanligtvis i åldern mellan 50 och 70 år och de mest förekommande symtomen är blod i urinen och flanksmärtor. Varför man får njurcancer är inte känt, men det finns ett klart samband med rökning och asbest. Njurcancer kan upIn the present thesis normal kidney tissue and renal cell carcinoma (RCC) were studied by cytogenetic and fluorescence in situ hybridization (FISH) methods to investigate chromosomal aberrations. In the first study, 4 samples of nonneoplastic kidney tissue were cultured for cytogenetic analysis and trisomy 7 was found in all cases in 3-15% of the cells. In the second study, cytogenetic analysis o

Second-hand Smoke, Cotinine Levels, and Risk of Circulatory Mortality in a Large Cohort Study of Never-Smokers.

BACKGROUND:: Exposure to second-hand smoke has been shown to be associated with increased cardiovascular mortality in several, but not all, epidemiologic studies. Our aim was to investigate the risk of circulatory death associated with exposure to second-hand smoke in never-smokers in a very large prospective study, the European Prospective Investigation into Cancer and Nutrition. A secondary aim

Normative dual energy X-ray absorptiometry data in Swedish children and adolescents.

Aim: To present normative dual energy X-ray absorptiometry data in healthy young Swedes. Methods: Included were 710 girls and 759 boys aged 6-30 years from southern Sweden. Bone mineral content, bone mineral density, bone size, lean body and fat mass were measured by dual energy X-ray absorptiometry in total body, lumbar spine, hip, arms and legs. Results: Swedish children had similar bone mass to

Thermosensitivity in a reconstructed microtic ear.

The aim of this study was to evaluate thermo-thresholds in autologous reconstructed microtic ears. Nineteen patients with unilateral microtia were investigated no less than two years after the last operation (3.6+/-1.7 years). Their normal corresponding ear acted as controls. Eight healthy children were also investigated to illustrate technical differences between measuring the two sides. Thermal

Cancer in immigrants as a pointer to the causes of cancer.

The early cancer studies on immigrants, which started to appear some 50 years ago, showed that the incidence in cancers changes to the level of the new host country in one or two generations. These findings were fundamental to the understanding of the environmental etiology of human cancer. Many immigrant groups originate from countries with no cancer registration, and, hence, the immigrant studie

Photon activation therapy of RG2 glioma carrying Fischer rats using stable thallium and monochromatic synchrotron radiation.

75 RG2 glioma-carrying Fischer rats were treated by photon activation therapy (PAT) with monochromatic synchrotron radiation and stable thallium. Three groups were treated with thallium in combination with radiation at different energy; immediately below and above the thallium K-edge, and at 50 keV. Three control groups were given irradiation only, thallium only, or no treatment at all. For animal

Long-term effects of acupuncture

Popular Abstract in Swedish Akupunktur är en mer än 2000 år gammal terapeutisk metod, som ingår i den traditionella kinesiska medicinen (TCM), för lindring av en del sjukdomar och symtom såsom smärta. Tunna, solida nålar instickes i så kallade akupunkturpunkter, oftast belägna i muskulaturen och utspridda över hela kroppen längs linjer som kallas meridianer. Det finns ett flertal olika sätt att teIn a retrospective follow-up study, n=202, long-term pain relief (>6 months) after a course of acupuncture treatments was found mainly among patients with chronic nociceptive pain while patients with neurogenic or psychogenic pain did not benefit much. In a placebo-controlled randomised single-blind long-term study with independent observer of chronic nociceptive low back pain, n=50, it was found

Measuring the migration of surgical specialists

Background: The lack of access to essential surgical care in low-income countries is aggravated by emigration of locally-trained surgical specialists to more affluent regions. Yet, the global diaspora of surgeons, obstetricians, and anesthesiologists from low-income and middle-income countries has never been fully described and compared with those who have remained in their country of origin. It i

Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants

The occurrence of a deoxyribonucleoside kinase in Drosophila melanogaster (Dm-dNK) with remarkably broad substrate specificity has recently been indicated (Munch-Petersen, B., Piskur, J., and Søndergaard, L. (1998) J. Biol. Chem. 273, 3926-3931). To prove that the capacity to phosphorylate all four deoxyribonucleosides is in fact associated to one polypeptide chain, partially sequenced cDNA clones

Epstein–Barr virus infection after adolescence and human herpesvirus 6A as risk factors for multiple sclerosis

Background and purpose: Infections with human herpesvirus 6A (HHV-6A) and Epstein–Barr virus (EBV) have been linked to multiple sclerosis (MS) development. For EBV, late infection has been proposed as a risk factor, but serological support is lacking. The objective of this study was to investigate how age affects the EBV and HHV-6A associated risks of developing MS. Methods: In this nested case–co

Elimination of 50% Iodine and Excellent Performance of Dye-Sensitized Solar Cell Enabled by TEMPO Radical Dendrimer-Iodide Dual Redox Systems

Detrimental effect of counter electrode corrosion, electrolyte leakage problem, and sublimation of iodine ions affect the performance and stability of dye-sensitized solar cells (DSSCs) based on a liquid redox electrolyte system. TEMPO/TEMPO+ is the most desirable one to replace the existing redox couples in liquid electrolyte owing to its rapid and reversible one electron kinetics, high diffusion

Assessing educational priorities in genetics for general practitioners and specialists in five countries: factor structure of the Genetic-Educational Priorities (Gen-EP) scale

Purpose: A scale assessing primary care physicians' priorities for genetic education (The Gen-EP scale) was developed and tested in five European countries. The objective of this study was to determine its factor structure, to test scaling assumptions and to determine internal consistency. Methods: The sample consisted of 3686 practitioners (general practitioners, gyneco-obstetricians, pediatricia