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The importance of family and friends for patients with mental health problems has been recognized over the past few years. Significant others (SO) of patients admitted to a psychiatric ward specializing in affective disorders and suicide prevention filled in a self-rating questionnaire concerning their burden as SOs, the Involvement Evaluation Questionnaire (IEQ). The aims of this study were twofo

The biogeography of speciation and what can be learned about the past mode of speciation from current biogeography of sister species are recurrent problems in evolution. We used a trait- and individual-based, eco-evolutionary model to simulate adaptive radiations and recorded the geographical overlap of species during and after evolutionary branching (speciation). We compared the spatial overlap a

Adipose tissue does not only store and release energy in response to hormones, it is also known as an endocrine organ, secreting important factors and hormones that influence for example appetite and insulin sensitivity. The association of type 2 diabetes with obesity has been known for quite some time. Understanding the cellular mechanisms of adipocyte function is of great importance in understan

Although groundwater serves as the predominant source of drinking water across many rural regions and certain urban areas of Rwanda, little is known about this resource. Anthropogenic impacts, such as faecal contamination, as well as geogenic water quality problems, including elevated arsenic, fluoride, iron, and manganese, are among the issues of concern for groundwater quality in Rwanda. Long-te

From November 12th to 13th in 1872, an extreme coastal flood event occurred in the south Baltic Sea. An unusual combination of winds created a storm surge reaching up to 3.5 m above mean sea level, which is more than a meter higher than all other observations over the past 200 years. On the Danish, German, and Swedish coasts, about 300 people lost their lives. The consequences of the storm in Denm

The fast-growing market of electric bikes (e-bikes) has introduced a paradigm shift in mobility with a promise to enhance the sustainability agenda. An in-depth understanding of transport quality of service (QOS) from the e-bike rider’s perspective is a promising approach to sustain the role of the e-bike in mobility. Level of service (LOS) is a method by which to quantify QOS for different transp

International collaboration is clearly a key priority in higher education andresearch (HER) policy and practice. The competition for students and excellentresearch and teaching staff is now a global one and this is reflected inthe increasing salience of phenomena such as the Shanghai and Times HigherEducation Rankings for monitoring the performance of HER institutions. Thischapter takes its point

The world has encountered numerous global crises, including epidemics, military conflicts, and economic collapse. Innovative digital technologies, such as Industry 4.0 (I4.0), can undoubtedly help improve industries’ operations during critical times. The dairy industry has seen an increment in technological adoption in the last few years. Adopting cutting-edge technologies is regarded as more feas

Mitochondria play a crucial role in metabolism and energy production by generating adenosine triphosphate (ATP) through oxidative phosphorylation. They also help maintain intracellular calcium levels, facilitate communication between the nucleus and cytoplasm, detoxify reactive oxygen species (ROS), and regulate apoptosis. Reversible acetylation of mitochondrial proteins is a key post-translationa

Introduction: Despite therapeutic achievements in haemophilia care, there is still the need to monitor and define personal treatment outcomes and document results to achieve the best possible care. Hence, a need for unbiased, timely and comprehensive real-world information exists to support informed shared decision-making regarding treatment and care. Aim: To describe a medical device for people l

The Svecofennian orogen in the Fennosandian Shield consists of several Palaeoproterozoic meta-igneous provinces that generally young progressively southwards and westwards. The understanding of the tectonic evolution of these different provinces is linked to the ability to constrain the timing of ductile deformation and metamorphism within them. In the western part of the orogen, in central Sweden

Wireless communication is evolving rapidly with ever more connected devicesand significantly increasing data rates. Since the invention of the smartphoneand the mass introduction of mobile apps, users demand more andmore traffic to stream music, watch high-definition video or to simply browsethe internet. This tremendous growth is more pronounced by the introductionof the Internet of Things (IoT)

Alltsedan incitamentsprogrammen introducerades i Sverige med inspiration från USA i mitten på 1900-talet har beskattningen av dem orsakat såväl tillämpningsproblem som debatt. Det handlar om de situationer där ett företag erbjuder anställda aktier i bolaget antingen i form av värdepapper eller personaloptioner. Den förra medför en rättighet direkt, medan den senare innebär en framtida rätt under fSince incentive plans first arrived to Sweden with inspiration from the U.S. in the middle of the 20th century the taxation of the programs have caused application problems as well as debate. The issue concerns situations where an employee is offered shares in the company based on securities or stock options. The employee hopes that he or she will get a piece of the profit in the future, while the

Climate warming has substantially advanced the timing of spring leaf-out of woody species at middle and high latitudes, albeit with large differences. Insights in the spatial variation of this climate warming response may therefore help to constrain future trends in leaf-out and its impact on energy, water and carbon balances at global scales. In this study, we used in situ phenology observations

To be able to survive in the long run the medical device industry of today needs effective development processes and ways to secure quality. These development processes and quality assurance processes must follow the different laws and regulations over the world depending on what market the organisations are established on. Organisations have been developing medical devices and systems over many y

Muscular dystrophy is a group of genetic disorders that lead to muscle wasting and loss of muscle function. Identifying genetic modifiers that alleviate symptoms or enhance the severity of a primary disease helps to understand mechanisms behind disease pathology and facilitates discovery of molecular targets for therapy. Several muscular dystrophies are caused by genetic defects in the components

Governments encourage cultural entrepreneurship in various ways, including by so-called tax incentives. Tax incentives are tax benefits for certain persons or activities. Most well known in relation to cultural policy are tax incentives for donations. The design of these tax incentives varies between countries. Not only may domestic tax incentives for donations be important for cultural organizati

BACKGROUND: Knowledge about the prevalence of women with breast implants is paramount in calculations of risks and in estimations of effects on screening and breast cancer treatment. Most of the estimations of prevalence made to date are rough and often based on sales data. The main aim of this study was to calculate the prevalence of breast implants in Swedish women. The secondary aim was to inve

Signal transduction and neurotransmitter release in the vertebrate central nervous system are confined to the structurally complex presynaptic electron dense projections called "active zones." Although the nature of these projections remains a mystery, genetic and biochemical work has provided evidence for the active zone (AZ) associated proteins i.e. Piccolo/Aczonin, Bassoon, RIM1/Unc10, Munc13/U

Neisseria meningitidis (meningococcus) is an important cause of meningitis and sepsis. Currently, there is no effective vaccine against serogroup B meningococcal infection. Host defense against neisseriae requires the complement system (C) as indicated by the fact that individuals deficient in properdin or late C components (C6-9) have an increased susceptibility to recurrent neisserial infections