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Monoclonal antibodies ofatumumab (anti-CD20) and alemtuzumab (anti-CD52) which are approved for usage in patients with chronic lymphocytic leukemia (CLL), efficiently activate the classical complement pathway. However complement is an exhaustible component and high doses of its activators may deplete complement-dependent cytotoxicity (CDC) potential, thus reducing the effect of repeated mAb dosing
Kerma-area product (KAP) meters have a pronounced energy dependence when measuring air KAP for lightly filtered X-ray beams (RQR). Today, it is also common with more heavily filtered beams. In this work, the energy dependence for lightly as well as heavily filtered beams (RQC) was investigated for several KAP meter models. The relative energy dependence of the readings of an external and an intern
We argue that it is not too early to begin the planning process for a next generation neutron source for Europe, even as the European Spallation Source is being constructed. We put forward three main arguments. Firstly, nowadays the period between the first scientific concept of a new facility being proposed and its actual realisation is approaching half a century. We show evidence for this. Secon
Virtual reality headsets, such as the HTC Vive, can be used to model objects, forces, and interactions between objects with high perceived realism and accuracy. Moreover, they can accurately track movements of the head and the hands. This combination makes it possible to provide subjects with precise quantitative feedback on their performance while they are learning a motor task. Juggling is a cha
Lantbruket rankas konsekvent som en av de mest riskfyllda sektorerna i Sverige såväl som i många andra delar av världen. Förutom lidande för den enskilde beräknas dödliga och icke dödliga skador i svenskt lantbruk kosta samhället 2 – 3 miljarder kr per år. I Sverige inträffade det cirka 5 000 olyckor på jordbruksföretag 2004. Detta innebar att minst en olycka inträffade på 8% av svenska gårdar som
Objective: To evaluate the influence of implant and prosthetic components on peri-implant tissue health. A further aim was to evaluate peri-implant soft-tissue changes following surgical peri-implantitis treatment. Materials and methods: Group discussions based on two systematic reviews (SR) and one critical review (CR) addressed (i) the influence of implant material and surface characteristics on
Background: Patients with perioperative myocardial injury are at risk of death and major adverse cardiovascular and cerebrovascular events (MACCE). The primary aim of this study was to determine optimal thresholds of preoperative and perioperative changes in high-sensitivity cardiac troponin T (hs-cTnT) to predict MACCE and mortality. Methods: Prospective, observational, cohort study in patients ≥
Here we report large-amplitude transit timing variations (TTVs) for AU Microcopii b and c as detected in combined TESS (2018, 2020) and CHEOPS (2020, 2021) transit observations. AU Mic is a young planetary system with a debris disk and two transiting warm Neptunes. A TTV on the order of several minutes was previously reported for AU Mic b, which was suggested to be an outcome of mutual perturbatio
This research study investigates the response of clay brick masonry with different crack widths before and after repointing subjected to water spray. In doing so, 3-course masonry prisms containing artificial cracks were exposed to a water spray during 23 hours of testing. Forty-nine cracked 3-course masonry prisms were prepared with a crack width varying between 0.3 mm and 0.9 mm, whereas thirtee
Activated transcription factor (TF) farnesoid X receptor (FXR) represses glucagon-like peptide-1 (GLP-1) secretion in enteroendocrine L cells. This, in turn, reduces insulin secretion, which is triggered when β cells bind GLP-1. Preventing FXR activation could boost GLP-1 production and insulin secretion. Yet, FXR's broader role in L cell biology still lacks understanding. Here, we show that FXR i
Endosomal entrapment is a key issue for the intracellular delivery of many nano-sized biotherapeutics to their cytosolic or nuclear targets. Photochemical internalisation (PCI) is a novel light-based solution that can be used to trigger the endosomal escape of a range of bioactive agents into the cytosol leading to improved efficacy in pre-clinical and clinical studies. PCI typically depends upon
Osteoarthritis (OA) is a common musculoskeletal disease that leads to deterioration of articular cartilage, joint pain, and decreased quality of life. When OA develops after a joint injury, it is designated as post-traumatic OA (PTOA). The etiology of PTOA remains poorly understood, but it is known that proteoglycan (PG) loss, cell dysfunction, and cell death in cartilage are among the first signs
2-amino-2-methyl-1-propanol (AMP) in dimethyl sulfoxide (DMSO) is a precipitating non-aqueous amine technology that can potentially lower the energy demand during CO2 removal from industrial flue gases compared to aqueous amine technologies. However, DMSO is hygroscopic and has a high possibility of absorbing water from humid flue gases, which can affect the physical properties of the system,
A small, nucleotide-binding domain, the ATP-cone, is found at the N-terminus of most ribonucleotide reductase (RNR) catalytic subunits. By binding adenosine triphosphate (ATP) or deoxyadenosine triphosphate (dATP) it regulates the enzyme activity of all classes of RNR. Functional and structural work on aerobic RNRs has revealed a plethora of ways in which dATP inhibits activity by inducing oligome
1 SPRING 2020 POLITICAL ECOLOGY, CRISIS AND IDENTITY (HEKN14 // Provisional) TEACHERS: Mads Barbesgaard (MB) [course coordinator] – mads.barbesgaard.2321@keg.lu.se Amr Ahmed (AA) -- amr.ahmed@keg.lu.se Mariko Takedomi Karlsson (MKT) – mariko.takedomi_karlsson@hek.lu.se Mathilde Martin (MM) -- mathilde.martin@keg.lu.se Rooms: F=Flygeln (first floor), R=Rio (fourth floor), M=Malmö (fourth floor), V=
https://www.keg.lu.se/en/sites/keg.lu.se.en/files/hekn14_provisional_schedule.pdf - 2026-06-24
Syllabus for SIM 202 Faculty of Social Sciences A. Syllabus for SIMS39 Social Sciences: Gender, Global Development and Postcolonialism, 15 credits, second cycle (A1N) The course was adopted by the Dean of the Faculty of Social Sciences on 7 January 2013, in accordance with the delegation of authorities at the Faculty of Social Sciences, reg.no. S2012/60. The syllabus was approved by the Committee
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/syllabussims39.pdf - 2026-06-24
ABSTRACT SOCIAL AND ENVIRONMENTAL CONSTRAINTS TO THE IRRIGATION WATER CONSERVATION MEASURES IN EGYPT Thesis submitted in partial fulfillment of the requirements of the Degree of Master of Science at Lund University, Sweden Nino Malashkhia Email: nino.malashkhia.052@student.lu.se November 2003 Supervised by Dr. Per Hillbur Malmö University, Sweden E-mail: Per.Hillbur@ts.mah.se ABSTRACT The present
https://www.lumes.lu.se/sites/lumes.lu.se/files/malashkhia_nino.pdf - 2026-06-24
Rapport vecka 14 (publicerad 2021-04-14) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 4 Aktuell status 4 10 postnummerområden med högst uppskattad förekomst av symtomatisk covid-19 14 april . . . . 6 10 postnummerområden med lägst uppskattad förekomst av symtomatisk covid-19 14 april . . . . 8 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . . . . .
https://www.covid19app.lu.se/sites/covid19app.lu.se/files/2021-04/rapport_vecka14_CoSS.pdf - 2026-06-24
Faculty of Social Science A. Syllabus for SELP02 Sociology of Law: Theories and Research Issues (15 credits, second cycle, A1N) The course was adopted by the Board of the Faculty of Social Science on the April 14 2011 and the syllabus was approved by the Sociology of Law unit on 17 march, 2011 and revised 15 of december 2011. B. Course Details The course is offered as a single subject course in so
https://www.soclaw.lu.se/en/sites/soclaw.lu.se.en/files/selp02syllabus.pdf - 2026-06-24
Microsoft Word - 4FCF957D3F5AB3E4B20E0B15064934A9.docx COSB30 China Today Autumn Semester 2023 Total pages: 904 Additional readings: 200 pages of readings selected to augment lectures, seminars, and discussions following documentary screenings. Books Joseph, William A. (ed.) (2019). Politics in China: An Introduction. Oxford: Oxford University Press (third edition). (Chapters: 1, 6, 8 Chapters 5,
https://www.ace.lu.se/sites/ace.lu.se/files/2023-05/COSB30_Literature_2023.pdf - 2026-06-24
