Filtyp
Background: People with hemophilia (PwH) or von Willebrand disease (VWD) are at risk of joint bleeding, which can lead to hemophilic arthropathy. Point-of-care musculoskeletal ultrasound (POC-MSKUS) is increasingly used to detect joint bleeds, but a comprehensive compilation of available independent scanning protocols and their respective measurement properties is missing. Objectives: This study a
Female drivers operating in the public transport sector are underrepresented in the literature on women’s mobility which largely addresses the fear of crime among female riders. Alternative modes of transport, as well as job opportunities, have nevertheless started to emerge as international and local ride-hailing firms mushroom across the globe in urban cities. The World Bank Group International
The morphology and the anatomy of the 13 species presently included in the genus Fulgensia were surveyed. Caloplaca aurea and C. paulii, two speciesregarded as closely related to Fulgensia by earlier authors, were also included in the study. Fulgensia was found to exhibit a great variation in both morphology and anatomy. The differences in size, shape and septation of the spores, in the anatomy of
Twenty-two female psychiatric outpatients with experiences of childhood sexual abuse took part in a two-year group therapy. All Completed therapy. At the end of therapy the women's psychiatric symptoms were reduced and their social interaction and adjustment were improved. They evaluated relationships to their children, partners and friends to be improved.
The peroxide response transcriptional regulator, PerR, is thought to contribute to virulence of group A Streptococcus (GAS); however, the specific mechanism through which it enhances adaptation for survival in the human host remains unknown. Here, we identify a critical role of PerR-regulated gene expression in GAS phagocytosis resistance and in virulence during pharyngeal infection. Deletion of p
Often, the research process is hidden under the dominant product, making all decisions, from the research question to the chosen method and theory, seem obvious in retrospect. Consequently, this paper has two tightly intertwined aims: to elucidate the research process of the study on which it is based; and to explore and discuss what this process temporally produced, namely, a focus group intervie
Popular Abstract in Swedish Bakterier av arten Streptococcus pyogenes kallas på svenska för grupp A streptokocker (GAS). Bakterien kan finnas hos människan utan att orsaka sjukdom (bärarskap) men också orsaka sjukdomar som t.ex. halsfluss och svinkoppor som även kallas impetigo. Detta är relativt milda infektioner men bör behandlas med antibiotika eftersom det kan uppstå följdsjukdomar en tid efteGroup A streptococcus (GAS) is one of the most common of bacterial pathogens infecting humans, frequently causing throat and skin infection. Some GAS strains have surface-expressed virulence factors called M proteins that bind human plasminogen with high affinity. Plasminogen is a central component of the human fibrinolytic system, and is bound by an M protein termed PAM through defined binding mo
Popular Abstract in Swedish SVENSK POPULÄRVETENSKAPLIG SAMMANFATTNING (SUMMARY IN SWEDISH) Vi kommer dagligen i kontakt med kemiska ämnen av olika slag. Med till exempel mat och dryck, läkemedel, tobaksrökning och miljögifter får vi i oss ämnen som kan vara skadliga för oss. Vi är dock utrustade med ett ordentligt reningsverk, framför allt är det levern som ser till att farliga ämnen bryts ner ochCytochrome P450 (CYP) is involved in the metabolism of the majority of clinically used drugs. We have studied the CYP mediated metabolism of quinoline 3-carboxamides, a group of synthetic immunomodulators in liver microsomal preparations from various species. Roquinimex, the lead compound, was found to be metabolised by CYPs to hydroxylated and demethylated metabolites. A similar metabolite patter
Disturbed indoor climate may in some cases be associated with illness. In the present paper, we report the results from a thorough investigation of office workers in Greenland, who developed skin and/or airway problems after moving into renewed offices.
Purpose: This study was intended to evaluate a multi-professional health-promoting and disease-preventive intervention organized as multi-professional senior group meetings, which addressed home-dwelling, independently living, cognitively intact elderly persons (80 +/-), by exploring the participants' experiences of the intervention. Method: The focus group methodology was used to interview a tota
The Vel antigen is present on red blood cells (RBCs) from all humans except rare Vel-negative individuals who can form antibodies to Vel in response to transfusion or pregnancy. These antibodies may cause severe hemolytic reactions in blood recipients. We combined SNP profiling and transcriptional network modeling to link the Vel-negative phenotype to SMIM1, located in a 97-kb haplotype block on c
Blood group ABO polymorphism was analysed in genomic DNA isolated from 150 blood donors by restriction endonuclease digestion of three polymerase chain reaction-amplified exons in the ABO genes and by sequencing of randomly selected samples. An anomalous O1 allele first described in a cancer cell line is now shown to account for approximately 40% of the O alleles described to date. This is 10 time
The evolution of cooperation requires benefits of group living to exceed costs. Hence, some components of fitness are expected to increase with increasing group size, whereas others may decrease because of competition among group members. The social spiders provide an excellent system to investigate the costs and benefits of group living: they occur in groups of various sizes and individuals are r
New basis sets of the atomic natural orbital (ANO) type have been developed for the main group and rare gas atoms. The ANO's have been obtained from the average density matrix of the ground and lowest excited states of the atom, the positive and negative ions, and the dimer at its equilibrium geometry. Scalar relativistic effects are included through the use of a Douglas-Kroll Hamiltonian. Multico
Background. Currently there is no consensus on the use of adjuvant radiotherapy (RT) in retroperitoneal sarcoma (RPS). We have analysed clinical outcomes in patients with localised RPS treated at two Scandinavian Sarcoma Group (SSG) centres: Haukeland University Hospital (HUH), Bergen, Norway and Skane University Hospital (SUH), Lund, Sweden to clarify the effects of adjuvant RT on local control a
Popular science summary: Do bacteria survive in humans by eating the defense molecules during the course of infection? Enterococcus faecalis (E. faecalis) is a pathogen that can be found in the human gut which causes a wide range of infections including urinary tract infections, cardiovascular infections and bacteremia (presence of bacterial cells in blood stream). These bacteria can also be fou
Thirty-eight women undergoing augmentation mammaplasty, consecutively operated on at the Department of Plastic and Reconstructive Surgery, Malmo, Sweden, were studied preoperatively regarding medical history, personality, psychosocial and psychiatric characteristics. Thirty-six of these patients were interviewed one year postoperatively. Thirty-three age-matched women operated on with minor surgic
Studies on music reading have provided insights into the cognitive processes in sight singing. However, there has been limited research on sight singing in a group setting. This study aims to assess how choral singers approach music reading as they perform previously unfamiliar choral scores together. We addressed (1) how singers’ gaze direction is distributed over staff systems, and (2) how their
Background: Maternally-inherited symbionts can induce pre-mating and/or post-mating reproductive isolation between sympatric host lineages, and speciation, by modifying host reproductive phenotypes. The large parasitoid wasp genus Cotesia (Braconidae) includes a diversity of cryptic species, each specialized in parasitizing one to few related Lepidoptera host species. Here, we characterized the in
Background: Deep learning methods are revolutionizing natural science. In this study, we aim to apply such techniques to develop blood type prediction models based on cheap to analyze and easily scalable screening array genotyping platforms. Methods: Combining existing blood types from blood banks and imputed screening array genotypes for ~111,000 Danish and 1168 Finnish blood donors, we used deep
