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We argue that there is a need for a more elaborate and sophisticated discussion of if, and then how, the public library fulfils its social role to con- tribute to democracy. Therefore, we have formed the Lund Critical Library Studies group with a shared interest of contributing to a more nuanced and rich discussion about public libraries. This allows us to engage in discussions on how the library
Group A Streptococcus (GAS) can be internalized by epithelial cells, including keratinocytes from human skin or pharyngeal epithelium. Internalization of GAS by epithelial cells has been postulated both to play a role in host defense and to provide a sanctuary site for GAS survival. The cholesterol-binding cytolysin streptolysin O (SLO) appears to enhance virulence in part by inhibiting GAS intern
Popular Abstract in Swedish Grupp A streptokocker (GAS) ger upphov till infektioner lokaliserade till svalg och hud såsom akut pharyngotonsillit (halsfluss), impetigo (svinkoppor), erysipelas (rosfeber) men även till invasiva (djupa) infektioner med allvarlig prognos, speciellt scarlatina (scharlakansfeber), puerperalfeber (barnsängsfeber), nekrotiserande fasciit och andra mjukdelsinfektioner samtGroup A streptococci (GAS) cause throat and skin infections, severe invasive diseases as well as the non-suppurative complications acute rheumatic fever and glomerulonephritis. GAS have retained susceptibility to betalactam drugs, but resistance to alternative antibiotics is of concern. In a large Iranian survey the carrier rates among symptom-free children and those with pharyngotonsillitis were
A division of labor with role specialization is defined as individuals specializing in a subtask during repetitions of a group task. While this behavior is ubiquitous among humans, there are only four candidates found among non-eusocial mammals: lions, mice, chimpanzees, and bottlenose dolphins. Bottlenose dolphins in the Cedar Keys, Florida, engage in role specialized “driver-barrier feeding”, wh
Group A streptococci, a common human pathogen, secrete streptokinase, which activates the host's blood clot-dissolving protein, plasminogen. Streptokinase is highly specific for human plasminogen, exhibiting little or no activity against other mammalian species, including mouse. Here, a transgene expressing human plasminogen markedly increased mortality in mice infected with streptococci, and this
The zinc chloride-mediated acetylation of the optically active silyl enol ether 2a gave the beta-diketone 3a (48%) together with the regio- and stereoselectively chlorinated compound 4 (27%). The yield of 4 increased to 70% by starting from the O-acetyl derivative 2c. The chlorination most likely occurs via neighboring group participation by the endo acetoxy group.
We construct a connected finite loop space of rank 66 and dimension 1254 whose rational cohomology is not isomorphic as a graded vector space to the rational cohomology of any compact Lie group, hence providing a counterexample to a classical conjecture. Aided by machine calculation we verify that our counterexample is minimal, i.e., that any finite loop space of rank less than 66 is in fact ratio
Popular Abstract in Swedish Grupp A streptokocker, på latin Streptococcus pyogenes, är bakterier som kan infektera människan. Halsfluss är den vanligaste och mest kända åkomman, men de orsakar också andra sjukdomstillstånd som svinkoppor och scharlakansfeber. I dagspressen kallas grupp A streptokocker då och då för mördarbakterier. Det epitetet har de fått för deras förmåga att vid vissa allvarligTemperature-dependent structure and function of group A streptococcal M proteins.This thesis describes the temperature-dependent structure of the members in the group A streptococcal M protein family. M proteins are cell-surface proteins that are important for the bacterial virulence and bind to a diverse set of human plasma proteins. The proteins are dimeric coiled-coil molecules, but temperature
Context. The HR 1614 is an overdensity in velocity space and has for a long time been known as an old (2 Gyr) and metal-rich ([Fe=H] +0:2) nearby moving group that has a dissolving open cluster origin. The existence of such old and metal-rich groups in the solar vicinity is quite unexpected since the vast majority of nearby moving groups are known to be young. Aims. In the light of new and signifi
CsrRS (or CovRS) is a two-component system implicated in the control of multiple virulence determinants in the important human pathogen, group A Streptococcus (GAS). Earlier studies suggested that extracellular Mg(2+) signalled through the presumed sensor histidine kinase, CsrS. We now confirm those findings, as complementation of a csrS mutant restored Mg(2+)-dependent gene regulation. Moreover,
The antigens of the ABO system were the first to be recognized as blood groups and actually the first human genetic markers known. Their presence and the realization of naturally occurring antibodies to those antigens lacking from the cells made sense of the erratic failure of blood transfusion hitherto and opened up the possibility of a safe treatment practice in life-threatening blood loss. Alth
A molecular phylogeny of the Lecanora rupicola group is presented, based on ITS sequence analyses. The study includes saxicolous and corticolous members of the Lecanora rupicola group as well as other Lecanora species with pruinose apothecia. A phylogenetic hypothesis for species in Lecanora s. lat. and various other genera in Lecanoraceae, based on an alignment-free distance estimation technique,
Modelling of pulverised wood flames in a laboratory vertical furnace was carried out. The aim was to gain deeper understanding of the combustion process and to validate a mathematical model to simulate the process. Pulverised wood combustion involves many different processes such as two-phase flow dynamics, drying and devolatilisation of the particles, oxidation of the volatile and formation and o
Background & objectives: We have earlier proposed that group A streptococcal (GAS) immunoglobulin binding surface proteins (IgGBPs) might trigger anti-IgG production and immune complex formation leading to glomerulonephritis. In the present study, cardiac tissue material from rabbits injected with heat-killed GAS was investigated. Methods: Rabbits were injected intravenously with 10(9) colony
A discrepancy in the ABO blood groups between a newborn child and her parents was identified. Serological and DNA investigative techniques were performed. A weak variant of B (B-w) was detected on the erythrocytes of the child, her grandmother and great-uncle. Adsorption-elution studies showed that their erythrocytes adsorb and yield anti-B on elution. The B-w antigenic strength of the A(1)B(w) ce
