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Aims. To investigate the effects of selective beta(2)- and selective beta(3)-adrenoceptor (AR) agonists on prostaglandin (PG) E-2-induced bladder hyperactivity in conscious free-moving rats. Methods. Female Sprague-Dawley rats were anesthetized for implantation of bladder, intravenous, and intra-arterial catheters. The effects of a beta(3)-AR agonist (CL316,243) on cystometric and cardiovascular p

Previous in vitro studies have implied that the Wnt-5a gene plays a role as a tumor suppressor. To explore the clinical relevance of this concept, 96 primary invasive breast carcinomas were stained with a novel anti-Wnt-5a antibody. Loss of Wnt-5a protein expression, evident in 44% of the invasive ductal carcinomas (n = 59), was significantly associated with higher histological grade (P = 0.01) an

Oscillations in plasma membrane potential play a central role in glucose-induced insulin secretion from pancreatic β-cells and related insulinoma cell lines. We have employed a novel fluorescent plasma membrane potential (ψp) indicator in combination with indicators of cytoplasmic free Ca2+ ([Ca2+]c), mitochondrial membrane potential (ψm), matrix ATP concentration and NAD(P)H fluorescence to inves

Purpose: To investigate the use of an affine-variance noise model, with correlated quantum noise and spatially dependent quantum gain, for the simulation of noise in virtual clinical trials (VCT) of digital breast tomosynthesis (DBT).Methods: Two distinct technologies were considered: an amorphous-selenium (a-Se) detector with direct conversion and a thallium-doped cesium iodide (CsI(Tl)) detector

There is a heavy dependence on cars for people living in rural areas and small towns. The countryside has so far been left out of the transition to carbon-free transport, and public transport shares are low in rural areas. New information and communication technology (ICT) solutions and autonomous vehicles (AVs) have the potential to improve the conditions for public transport in rural areas, as t

A semiconductor-to-metal transition in N = 7 armchair graphene nanoribbons causes drastic changes in its electron and phonon system. By using angle-resolved photoemission spectroscopy of lithium-doped graphene nanoribbons, a quasiparticle band gap renormalization from 2.4 to 2.1 eV is observed. Reaching high doping levels (0.05 electrons per atom), it is found that the effective mass of the conduc

A variational approach, based on a discrete representation of the chain, is used to calculate free energy and conformational properties in polyelectrolytes. The true bond and Coulomb potentials are approximated by a trial isotropic harmonic energy containing force constants between all monomer-pairs as variational parameters. By a judicious choice of representation and the use of incremental matri

The early molecular response to severe traumatic brain injury (TBI) was evaluated using biopsies of structurally normal-appearing cortex, obtained at location for intracranial pressure (ICP) monitoring, from 16 severe TBI patients. Mass spectrometry (MS; label free and stable isotope dimethyl labeling) quantitation proteomics showed a strikingly different molecular pattern in TBI in comparison to

IgA1 mesangial deposition is the hallmark of IgA nephropathy and Henoch-Schönlein purpura, the onset of which often follows infections. Deposited IgA has been reported as polymeric, J chain associated, and often, hypogalactosylated but with no information concerning the influence of the IgA repertoire or the link between immune stimuli and IgA structure. We explored these issues in the α1KI mouse

weAdventure Outdoor adventures powered by locals Kristofer Söderström weAdventure Outdoor adventures powered by locals Kristofer Söderström Hello everyone! My name is Kristofer. Together with my partner Jeremy, which is currently in Nepal, we’re part of weAdventure, the online marketplace for adventure and eco travel. 1,235,000,000 Did you know that, just in 2016 more than one billion people trave

https://www.climate-kic.lu.se/sites/climate-kic.lu.se/files/7._weadwenture.pptx - 2026-05-06

4 June 2025 13:00 to 15:00 | Workshop Creating a research network to foster woman's partcipation in technoscience. An online lecture and on-site seminar in the serie Girls Just Want To Have Sc(AI)ence.Topic: We Should All Be Feminists in Software EngineeringWhen & where:  4 June May 202513.00 - 14.00: Hybrid lecture on zoom14.15 to 15.00 On-site lecture plus workshop in M:Teknodromen, Klas Anselms

https://www.staff.lu.se/calendar/girls-scaience-3-we-should-all-be-feminists-software-engineering - 2026-05-06

Theoretical calculations of reaction kinetics were done for one‐step reactions catalyzed by cells immobilized in spherical beads. The reactions catalyzed by free cells were assumed to obey Michaelis–Menten kinetics for a one‐substrate reaction. Both external (outside the beads) and internal (inside the beads) mass transfer of the substrate were considered for the immobilized preparations. The theo

This study uses a model-based design approach (CFD coupled to well-established emulsification correlations) to investigate how to choose the valve dimensions of a high-pressure homogenizer so as to achieve intensified drop breakup without increasing the power consumption. Results show how design modifications influence the thermodynamic efficiency of the homogenizer via two effects, a friction fac

Introduction The aim of this study was to describe the complications of ureteroscopy (URS) and to investigate whether performing URS outside normal working hours leads to increased risk for clinically significant complications. Material and methods A cohort of 486 consecutive patients treated with URS, with a total of 567 sessions between 2009 and 2015 at Helsingborg/Ängelholm Hospital, Sweden, wa

The ongoing Internet of Things revolution has led to strong demand for low-cost, ubiquitous light sensing based on easy-to-fabricate, self-powered photodetectors. While solution-processable lead-halide perovskites have raised significant hopes in this regard, toxicity concerns have prompted the search for safer, lead-free perovskite-inspired materials (PIMs) with similar optoelectronic potential.

From trash to treasure – detta är återbruk Vi lever idag i ett samhälle där ”slit och släng” är vanligt för bland annat kläder, möbler och leksaker. När något går sönder eller en nyare modell finns ute på marknaden slängs många föremål som hade kunnat användas (återbrukas). Att slänga föremål som fungerar eller hade kunnat lagas, skadar miljön. Det finns en tro om att återbruk av föremål inte är fToday we wear and tear objects and materials, in line with the linear economy. By instead reusing, the need for new production decreases, and so the extraction of raw materials, greenhouse gas emissions and generation of waste. By increasing the reuse rate, we can strive towards a circular economy and climb EUs waste hierarchy. The aim of this master’s dissertation was to study different business