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Objective: The aim of the first Nordic mantle cell lymphoma (MCL) protocol was to study the clinical significance of an augmented CHOP induction chemotherapy followed by high-dose chemotherapy and autologous stem cell transplantation (ASCT) and to examine the prognostic significance of stem cell contamination rates in newly diagnosed patients with MCL. Patients and methods: Forty-one newly diagnos

Serum cystatin C concentration correlates negatively with glomerular filtration rate as well as or better than that of serum creatinine, suggesting a constant formation, and elimination from extracellular fluid mainly by glomerular filtration. It is not known, however, how well the renal plasma clearance of this 13-kDa basic polypeptide matches the glomerular filtration rate. This was investigated

Circular RNAs (circRNAs) are a class of RNAs that is under increasing scrutiny, although their functional roles are debated. We analyzed RNA-seq data of 348 primary breast cancers and developed a method to identify circRNAs that does not rely on unmapped reads or known splice junctions. We identified 95,843 circRNAs, of which 20,441 were found recurrently. Of the circRNAs that match exon boundarie

Purpose: The eyelid is commonly dissected and divided in the process of, for example, blepharotomy, entropion repair, or when preparing a full-thickness eyelid flap to reconstruct a tumor defect. No study has yet been conducted to examine how perfusion in an eyelid is affected by dissection, using modern imaging techniques. Methods: The eyelid was divided with a 10-mm vertical incision, 5 mm from

AbstractThe cerebellum is an important part of the brain and in very preterm infants the cerebellum is smaller at term equivalent age compared to that of infants born at term.Hypothesis and aims: The general hypothesis is that preterm birth per se causes cerebellar underdevelopment and that certain events following preterm birth, either complications or treatments, can aggravate the underdevelopme

Activation of polymorphonuclear leukocytes (PMNs) and adhesion to the endothelial lining is a major cause of edema formation. Although known to be dependent on the function of β2 integrins (CD11/CD18), the precise mechanisms by which adherent PMNs may impair endothelial barrier capacity remain unclear. Here, the role of transmembrane signaling by β2 integrins in PMN-induced alterations in tight ju

Background: Good care of the dying has been defined as being able to die in the place of your choice, free from pain, cared for with dignity and supported by the best possible care. This definition underpinned the development of the ‘10/40 Model’ of care for the dying, in 2013. The model includes 10 ‘Key Principles’ that underpin 40 ‘Core Outcomes’ of care. It was necessary to update consensus on

Att gårdsförsäljning av alkoholdrycker ska bli en verklighet i Sverige är något som många vill se. För att gårdsförsäljningen ska kunna existera vid sidan om det svenska alkoholmonopolet krävs att den är förenlig med rådande EU-rätt. Centralt för den EU-rättsliga regleringen är upprätthållandet av en inre marknad där det råder fri rörlighet för varor. Artikel 37 i Fördraget om Europeiska unionens On-farm sales of alcoholic beverages becoming a reality in Sweden many wish to see. For on-farm sales to coexist with the Swedish alcohol monopoly, compatibility with current EU law is required. Central to EU legal regulation is the maintenance of an internal market with the free movement of goods. Article 37 of the Treaty on the Functioning of the European Union (TFEU) regulates state trading mon

Linking conflict events and cropland development in Afghanistan, 2001 to 2011, using MODIS land cover data and Uppsala Conflict Data Programme This thesis describes changes in land cover between 2001 and 2011 in Afghanistan, and analyzes the influence of conflict events on cropland development. How did fighting intensity affect cropland areas in Afghanistan, did cropland areas decrease or incre

Modern well-insulated and highly glazed buildings experience increased overheating, even in cold climates. Buildings hold the biggest share of the world’s energy use, and current climate crisis can exacerbate future need for cooling. The study strives to analyse passive solar shadings on a south-oriented façade, having predetermined that external and internal shadings’ main function is solar heat

In this thesis the prospect of using cereal oil as a natural emulsifier after enzymatic treatment was investigated. A lipase was used in both free and immobilized form. Hydrolysis reactions were carried out using two different oil in water (O/W) emulsions. Microscopy of emulsion formation was visualized, and droplet size was obtained using a particle size distribution analyzer (PSD). Lipid extract

Objectives. Primary hyperparathyroidism (PHPT) is associated with low bone mineral density (BMD) and increased risk of osteoporotic fractures. This study investigated whether the IGF-I axis and thyroid hormones are associated with BMD and osteoporotic fractures before and after parathyroidectomy (PTX). Materials and methods. Forty-five patients with mild PHPT were examined before and 1 year after

ObjectivesFrequent blood sampling in vulnerable patient groups, such as prematurely born infants, can lead to significant blood loss and increased transfusion needs. Current pre-analytical technology requires comparably large blood volumes and leads to discarding of cells. This study investigates a device prototype enabling in-line sampling where cell-reduced plasma for clinical chemistry analyses

During the summer of 2005 more than 80 million articles of clothing from China, were being held in European harbours. This was a consequence of a striking increase of imported textile and clothing articles from China since the turn of the year, which was the time when all quantitative restrictions were extincted on these products. To protect its own market, the EU therefore reintroduced import quo

This study examines regional integration in Africa with a focus on the Common Market for Eastern and Southern Africa, COMESA. COMESA, with roots that go back to the beginning of the 1980’s, is one of the largest and most diverse areas for regional integration in Africa and has currently 19 member countries. The goal of the COMESA co-operation is to become a fully integrated area by the year 2025 t

Den svenska narkotikapolitiken har sedan den andra halvan av 1900-talet varit föremål för en aktiv debatt. Det fastslagna målet för denna politik har varit ett narkotikafritt samhälle. För att uppnå detta mål har flera åtgärder vidtagits. En av dessa åtgärder var kriminaliseringen av eget bruk som skedde 1988 med en påföljande straffskärpning 1993. Denna uppsats behandlar den svenska narkotikala

Adjungerad professor Kontaktinformation E-post: linda [dot] knutsson [at] med [dot] lu [dot] seOrganisation Medicinsk strålningsfysik, Lund Hämtställe: 32 WebbplatsLinda Knutssons profil i Lunds universitets forskningsportalAndra roller Projektledare MR Physics Profilområdesmedlem Lunds lasercentrum, LLC Profilområdesmedlem LTH profilområde: Avancerade ljuskällor Medlem i Strategiskt forskningsomr

https://www.msf.lu.se/linda-knutsson - 2026-05-06

www.lightforchildren.com LIGHT FOR CHILDREN GHANA UNIVERSITY PARTNERSHIPS Light for Children (LIFOC) is a registered organization without religious or political affiliation. It seeks the welfare of needy and disadvantaged children and also focuses on community and humanitarian services. Light for Children works with international volunteers and interns because only a very limited number of local v

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/placements_for_interns.pdf - 2026-05-07

Background: Osteoarthritis (OA) is a progressive, chronic disease characterized by articular cartilage destruction. The pro-inflammatory cytokine IL-17 levels have been reported elevated in serum and synovial fluid of OA patients and correlated with increased cartilage defects and bone remodeling. The aim of this study was to characterize an IL-17-mediated articular cartilage degradation ex-vivo m

Atmospheric carbon dioxide enrichment (eCO2) can enhance plant carbon uptake and growth1–5, thereby providing an important negative feedback to climate change by slowing the rate of increase of the atmospheric CO2 concentration6. Although evidence gathered from young aggrading forests has generally indicated a strong CO2 fertilization effect on biomass growth3–5, it is unclear whether mature fores