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Homozygosity for the IgG2 subclass allotype G2M(n) protects against severe infection in hereditary C2 deficiency

Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish pat

The derivation of first- and second-order backpropagation methods for fully-connected and convolutional neural networks

We introduce rigorous theory for deriving first and second order backpropagation methods for Deep Neural Networks (DNN) whilst satisfying existing theory in DNN optimization. We begin by formally defining a neural network with its respective components and state the first and second order chain rule with respect to its partial derivatives. The partial derivatives in the chain rule formula are rela

The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease

In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses

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Les amie Marie et johanna pensent de faire un voyagr en italie. Marie veux couche dans la solei et Johanna aime les garcon d´italie. Les dames iront mais ses sac son trés grands. Elles ont trop plein de bagage et c´ést trés facile quand elles voyageraient dans la voiture. Mais c´ést solvera et les amie conduent a italie. Quand Marie et Johanna vont a la hôtel elles voudront une chambre. Elles ont

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/stade_c/Cathy.txt - 2026-05-25

N-glycans and the N terminus of protein C inhibitor affect the cofactor-enhanced rates of thrombin inhibition

Protein C inhibitor (PCI) is a serine protease inhibitor, displaying broad protease specificity, found in blood and other tissues. In blood, it is capable of inhibiting both procoagulant and anticoagulant proteases. Mechanisms that provide specificity to PCI remain largely unrevealed. In this study we have for the first time provided a full explanation for the marked size heterogeneity of blood-de

Four modes of adhesion are used during Helicobacter pylori binding to human mucins in the oral and gastric niches

Background: Helicobacter pylori causes peptic ulcer disease and gastric cancer, and the oral cavity is likely to serve as a reservoir for this pathogen. We investigated the binding of H. pylori to the mucins covering the mucosal surfaces in the niches along the oral to gastric infection route and during gastric disease and modeled the outcome of these interactions. Materials and Methods: A panel o

Applied remote sensing 2016 becc web oct2

Advanced PhD course in remote sensing of vegetation and environment Applied land remote sensing, 3 credits Jonas Ardö, Lars Eklundh, Karin Hall et al Department of Physical Geography and Ecosystem Science Lund University October 2, 2015 The aim of this course is to provide students with skills in applied remote sensing with focus on applications regarding vegetation in terrestrial environments. We

https://www.cec.lu.se/sites/cec.lu.se/files/applied_remote_sensing_2016_becc_web_oct2.pdf - 2026-05-27

Aspectuality, temporality and modality: a relevance-theoretic analysis of some pragmatic markers in Mandarin Chinese

Aspecuality, temporality and modality: a relevance-theoretic analysisof some pragmatic markers in Mandarin Chinese It is generally agreed that in Mandarin Chinese, tense (at least absolute tense) is not expressedmorphologically but there is a number of verbal and sentence-final particles that express aspect and mood. These (in particular the aspectual ones) have been studied rather extensively thr

Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin

Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel

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No Slide Title Tense - aspect in early stages of child L2 acquisition Suzanne Schlyter Lund University Sweden Eurosla 18 Aix-en-Provence sept 2008 Child second language acquisition - chL2 Child second language acquisition, chL2: start 3 – 8 years Is chL2 more like L1 or more like adL2 acquisition? Role of the Age of Onset of the Acquisition? Unsworth (2005), Meisel (2006, 2008), Bonnesen (2008), T

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_sprakutv_franska/Eurosla18_childL2.ppt - 2026-05-25

Expedition 391 summary

Hotspot tracks (chains of seamounts, ridges, and other volcanic structures) provide important records of plate motions, as well as mantle geodynamics, magma flux, and mantle source compositions. The Tristan-Gough-Walvis Ridge (TGW) hotspot track, extending from the active volcanic islands of Tristan da Cunha and Gough through a province of guyots and then along Walvis Ridge to the Etendeka flood b

Determination of specific surface by the BET method

The theoretical background of the adsorption isotherm equation of Brunauer, Emmett and Teller is reviewed, together with the experimental techniques available for measuring physical adsorption of gases by solids. Examples are given to show how such measurements are used to determine the specific surface of constructional materials.