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Popular Abstract in Swedish Tillväxtfaktorer kan förbättra cellöverlevnad och funktion i djurmodeller av Parkinson’s sjukdom. En av de vanligaste sjukdomarna i nervsystemet är Parkinson’s sjukdom. Den uppkommer genom att man gradvis förlorar en viss grupp av nervceller som använder signalsubstansen dopamin, vilket i sin tur leder till brist på dopamin i målområdet i hjärnan, striatum. Detta resulParkinson’s disease is characterized by progressive degeneration of the nigrostriatal dopamine system, which results in tremor, rigidity, akinesia and postural abnormalities. New therapeutic strategies are aimed at halting the neurodegenerative process or restoring the system by transplantation of fetal dopamine neurons. We have investigated the potential of the neurotrophic factors glial cell lin

The European Spallation Source (ESS) is the European common effort in designing and building a next generation large-scale user facility for studies of the structure and dynamics of materials. The proposed schematic layout of the ESS facility is based on a linear driver (linac) directing the proton beam (5 MW of 2.5 GeV) of 2.8 ms long pulses with a 20 Hz on a tungsten target where neutrons are pr

Background The pattern of cancer in long-term survivors from childhood cancer has not been investigated comprehensively. Methods We obtained a cohort of 47 697 children and adolescents aged 0-19 years with cancer as defined by the country-wide cancer registries of Denmark, Finland, Iceland, Norway, and Sweden during 1943-2005. Cohort members were followed through age 79 years for subsequent primar

Degrowth is an academic concept and activists' niche project in Europe and other early-industrialized parts of the world aiming to reframe the current sustainability challenge of declining environmental and unjust social conditions. Its emphasis is on the radical transformation of the current societal-economic structure in order to achieve inherently sustainable conditions. There are various d

The expansion of Swedish wind energy grid has come at the cost of environmental, economic and social controversy, in which the issue of landscape quality change plays a prominent role. Tourism, an industry highly reliant on visual consumption of the landscape, is especially sensitive to this change. Scholars have repeatedly harvested evidences of a weak, but negative correlation between wind power

Haloacid dehalogenase (HAD)-like hydrolases represent a vast superfamily characterised by their ability to form covalent enzyme-substrate intermediates facilitating the cleavage of C-Cl, C-P, or CO-P bonds. Within this work one member of this superfamily, HAD from Thermotoga neopolitana (HADTn) exhibiting a phosphatase (P-O bond cleavage) like activity was investigated in the context of altering t

Doftreceptor Or22a och dess betydelse för äggläggning hos bananflugor Vanliga bananflugor har länge använts som testorganismer inom biologisk forskning, så som neurobiologi. Anledningen till detta är att de har ett nervsystem som är lättillgängligt men enklare uppbyggt än däggdjurs (Stocker, 1994,). Luktsinnet hos bananflugor sitter i antennerna och i de maxillära papillerna, som sitter vid flugaThe fruit fly Drosophila melanogaster has a well-studied olfactory system. A crucial part of the olfactory system is the olfactory sensory neurons (OSNs). One type of these OSNs, Ab3a, expresses the Odor receptors (ORs) Or22a and Or22b. Or22a is known to play an important role for behaviors like oviposition, but no strong ligand has been found for Or22b. Recent studies have shown that D. melanogas

Pulsed electric field (PEF) treatment is a non-thermal process which has a wide range of beneficial effects in food processing. The application of pulsed electric field treatment relevant for this work is as pre-treatment on basil leaves before the drying process. It has been proven that PEF treatment can significantly reduce the drying time due to the electroporation of the guard cells of stomata

PFOS (Perfluoroktansulfonat)-föroreningar har hittats på många ställen i Sverige och i resten av världen, därför finns det ett stort intresse och behov av att kunna kartlägga föroreningarna med fler metoder än vad som finns till-gängligt i dagsläget. Det här examensarbetet har som syfte att undersöka resistivitets- och IP (induced polarization)-mätningars lämplighet att kartlägga PFOS vid en brand

In the present time, the rate of environmental degradation requires us to use all available means to avoid further damage and restore the environment to the best of our possibilities. Education is an important channel to promote environmentalism and sustainability, and to promote pro-environmental individual decisions, especially regarding consumption and purchasing patterns. The case study analys

Antimicrobial resistance is according to the World Health Organization (WHO) one of the most rapidly growing threats to world health. According to a recently published WHOreport, drug resistant microbials could be responsible for up to 10 million annual deaths by the year 2050 unless drastic measures are taken such as decreasing misuse and developing new antibiotics. This work explores the possibi

Studier av palaeostormfloder ger bakgrund till inom vilka intevall stormar av olika storlek förväntas återkomma och träffa olika områden. Denna information kan användas vid modellering, riskbedömning och stadsplanering. Genom att använda de marina ekvationerna av Nittrouer och Sternberg (1981; The formation of sedimentary strata in an allochthonous shelf environment: the Washington continental sheStudies of palaeostorm surges provides background into at what frequencies storms of different magnitudes are expected to return and hit different areas. This information can be used when modelling, doing risk assesments and city planing. Using the marine equations of Nittrouer and Sternberg (1981; The formation of sedimentary strata in an allochthonous shelf environment: the Washington continenta

Hur kan ett nytt konstmuseum i Amiralsstaden bli en generator för stadens framtida utveckling? Mitt intresse att angripa denna fråga har uppstått i ett debattklimat där inblandade aktörer argumenterar för sina respektive ståndpunkter i lokaliseringsfrågan, men där avsaknad av konkreta visioner gjort att diskussionen nått en återvändsgränd. Med detta examensarbete vill jag med hjälp de verktyg och How can a new art museum in Amiralsstaden become a generator for city development? My interest in tackling this issue begun in a debate where stakeholders argue for their respective positions on the issue of location, but where the lack of concrete visions has led to the discussion reaching a dead end. In this thesis, I intend to utilize the tools and processes developed during my studies to make

Background: Knowledge sharing within an organization is one of the main focuses of the knowledge management research field. In today’s globally dispersed business units, and multinational corporations (MNCs), information and communication technology (ICT) tools play an essential role in facilitating knowledge sharing. Previous research has argued the vital role informal contexts as well as physica

While renewable energy output in the World increases, Russia shows an opposite trend, consisting of a highly engrained fossil fuel-driven economy with very little State priority towards diversifying its energy supply. Accordingly, although wind energy represents only a niche market, it is more economically viable to electrifying Northern peripheral communities than connecting them to the national

The increasing demands on the vehicle market regarding cost effectiveness, efficient production and innovative solutions create an unforgiving environment for the suppliers. Haldex has developed Haldex Way, a management and improvement framework focused on lean production to meet these demands. Although lean methodologies are utilized at Haldex, Haldex Way has currently issues with consistency and

Populärvetenskaplig sammanfattning: Naturkatastrofer är något som Sverige är relativt förskonat från. Massrörelser, alltså markrörelser i jordtäcke eller berg såsom lerskred, slamströmmar och bergras, är däremot relativt vanligt förekommande runt om i landet. Det är dessutom så att frekvensen av den här typen av fenomen förväntas öka i Sverige till följd av framtida klimatförändringar. De områdenRecent studies indicate a widespread but largely overlooked hazard of contaminant mobilisation and transport in connection to mass movement activity into surface water systems in Sweden. Concerns are exacerbated by predicted effects of climate change, which suggest national increases in rates of precipitation, pore water pressures, run -off, erosion and mass movement occurrence. In this study, the

Uppsatsens huvudsakliga syfte är att utreda om det med härledning till EU-rätten och EUD:s rättspraxis kan utrönas en gränsdragning för när en privatperson till-handahåller tjänster kan anses göra detta i egenskap av en beskattningsbar person och följaktligen faller transaktionen under mervärdesskatterättens tillämpnings-område. Utredningens analytiska utgångspunkt utgår från det ekonomiska sam-liThis essay's main purpose is to examine when a private individual, who provides services, can be considered to do this as a taxable person and therefore falls under the scope of VAT. This survey's analytical starting point is based on the economic concept collaborative consumption. The term describes an economic model which is based on the coordination of individuals' consumption needs

The Maha Oya river mouth, located on the west coast of Sri Lanka, is seasonally closed by a sand bar formed at the river mouth due to little rainfall and thus little river discharge. A new Outlet, located just north of the Maha Oya river mouth, was created by the 2004 tsunami. The Outlet remains open all year because of its location in the lee of an offshore breakwater. When the Maha Oya river mou

Titel: CSR i SMEs – En studie om uppfattning, motiv och hinder Seminariedatum: 30 maj 2013. Ämne/Kurs: Magisteruppsats Civilekonomprogrammet - Företagsekonomi, FEKN90 30 hp Författare: Henrik Halling, Erik Karlsson Handledare: Christine Blomqvist Fem nyckelord: corporate social responsibility (CSR), små och medelstora företag (SMEs), motiv, hinder och uppfattning. Syfte: Syftet med uppsatTitle: CSR in SMEs – A study of perception, motives and barriers. Seminar date: may 30th 2013 Course: Master Thesis in Business Administration - FEKN90 30 (ECTS) Authors: Henrik Halling, Erik Karlsson Advisor: Christine Blomqvist Five key words: corporate social responsibility (CSR), small and medium enterprises (SMEs), motives, barriers and perception. Purpose: The purpose of this stud