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The bacterial stringent response is a key regulator of bacterial virulence, biofilm formation and antibiotic tolerance, and is a promising target for the development of new antibacterial compounds. The intracellular nucleotide (p)ppGpp acts as a messenger orchestrating the stringent response. A synthetic peptide 1018 was recently proposed to specifically disrupt biofilms by inhibiting the stringen

Many items of culture which are conveyed from one culture to another may take verbal form, and then constitute what Jakobson called "translation proper." If such diffusions involve a co-occurrent change of semiotic systems, they are of such a different nature, that we better reserve another term for it: transposition. Whether or not accompanied by transpositions, such as pictures, translational ev

Differences in national legislations can affect the international competitiveness of an industry. For example, stringent EU regulations on animal welfare and environmental protection are often said to be a cost disadvantage for EU producers competing on the global market. However, in recent years, powerful retailers and food processors have started to impose requirements on downstream producers th

The tightened security restrictions after the “911” terrorist attacks must clearly have repercussions for privacy, almost regardless of how this term is conceptualised. The notably fluid essentials of the privacy-term makes it hard to evaluate the actual impact of new regulation as a shared point of reference is in fact lacking (its definition has been a popular topic for vicious debate and acute

In the last two decades, health promotion strategies have gained significant attention in end-of-life care contexts—engendering greater focus on community and informal care in policy and healthcare spheres in liberal welfare-states. The emergence of health-promoting palliative care (HPPC) in the Nordic context presents a unique challenge to the abiding social contract of care which emphasizes the

We all know that conflict creates displacement. Life becomes untenable in different ways, and people are forced to move; the majority ending up as internally displaced people within the nation-state, while others wind up in refugee camps in neighboring countries, and a very few seek asylum in faraway places. The recent war in Ukraine and the conflict in Syria since 2011 seemingly fit into this cla

This paper analyses experiences of depression and antidepressant use within a neoliberal society. The paper is based on interviews with mainly women using antidepressants in Sweden and makes use of the post-political as conceptualized by Chantal Mouffe as a framework. I find that depression is reduced to a state, a diagnosis. In comparing with Nancy Friedan who gave the depression and despair Amer

By examining all emission lines of Fe II in high resolution satellite spectra of the symbiotic star RR Tel we have made a systematic study of fluorescence lines in the ultraviolet wavelength region 1200-3000 Å. We list 33 energy levels of Fe II that are selectively excited in the stellar system by photons from strong lines of H, He II, Si III, O III, C IV, O V, Ne V, and O VI. All energy levels li

WHO estimated in 2002 that 1.4 million children in the world would die from preventable diseases (World Health Organization, 2010). Each child is, or should be, immunized according to their national immunization schedule, which regulates i.e. vaccines and doses. Problems emerge when immigrant children should be transferred from one national vaccination schedule into another. This problem is quite

The measurement and application of residual dipolar couplings (RDCs) in solution NMR studies of biological macromolecules has become well established over the past quarter of a century. Numerous methods for generating the requisite anisotropic orientational molecular distribution have been demonstrated, each with its specific strengths and weaknesses. In parallel, an enormous number of pulse schem

A light-induced photoluminescence (PL) enhancement in surface-deposited methylammonium lead iodide (CH3NH3PbI3) perovskites was investigated in detail using time-resolved luminescence microscopy. We found the PL intensity to increase up to three orders of magnitude upon light illumination with an excitation power density of 0.01-1 W cm(-2). The PL enhancement is accompanied by an increase of the P

BACKGROUND: The dystrophin gene, which is mutated in Duchenne muscular dystrophy (DMD), encodes a large cytoskeletal protein present in muscle fibers. While dystrophin in skeletal muscle has been extensively studied, the function of dystrophin in vascular smooth muscle is less clear. Here, we have analyzed the role of dystrophin in injury-induced arterial neointima formation. METHODOLOGY/PRINCIPAL