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The BOADICEA breast cancer (BC) risk assessment model and its associated Web Application v3 (BWA) tool are being extended to incorporate additional genetic and non-genetic BC risk factors. From an online survey through the BOADICEA website and UK, Dutch, French and Swedish national genetic societies, we explored the relationships between the usage frequencies of the BWA and six other common BC ris

Background: Growing evidence suggests a role of occupation in the emergence and manifestation of dementia. Occupations are often defined by complexity level, although working environments and activities differ in several other important ways. We aimed to capture the multi-faceted nature of occupation through its measurement as a qualitative (instead of a quantitative) variable and explored its rel

Definite progress has been made in the exploration of myelodysplastic syndromes (MDS) by flow cytometry (FCM) since the publication of the World Health Organization 2008 classification of myeloid neoplasms. An international working party initiated within the European LeukemiaNet and extended to include members from Australia, Canada, Japan, Taiwan and the United States has, through several worksho

Resting-state fMRI has proven to entail subject-specific signatures that can serve as a fingerprint to identify individuals. Conventional methods are based on building a connectivity matrix based on correlation between the average time course of pairs of brain regions. This approach, first, disregards the exquisite spatial detail manifested by fMRI due to working on average regional activities, se

Rare-earth doped nanoparticles can exhibit narrow optical and spin linewidths at low temperatures. These outstanding properties for nanomaterials make them attractive for quantum technologies based on optically addressable spins such as quantum memories and computers. Although accurate linewidth measurements have been reported using, for example, spectral hole burning or photon echo techniques, so

Induction of SRY box transcription factor 9 (SOX9) has been shown to occur in response to kidney injury in rodents, where SOX9-positive cells proliferate and regenerate the proximal tubules of injured kidneys. Additionally, SOX9-positive cells demonstrate a capacity to differentiate toward other nephron segments. Here, we characterized the role of SOX9 in normal and injured human kidneys. SOX9 exp

BACKGROUND: Movement disorders are frequent in patients with inborn errors of metabolism (IEMs) but poorly recognized, particularly by nonmovement disorder specialists. We propose an easy-to-use clinical screening tool to help recognize movement disorders.OBJECTIVE: The aim is to develop a user-friendly rapid screening tool for nonmovement disorder specialists to detect moderate and severe movemen

Introduction A second peak of inhibitors has been reported in patients with severe hemophilia A (HA) aged >50 years in the United Kingdom. The reason for this suggested breakdown of tolerance in the aging population is unclear, as is the potential impact of regular exposure to the deficient factor by prophylaxis at higher age. No data on hemophilia B (HB) have ever been reported. Aim The ADVANCE W

Authors rely on a range of devices and techniques to attract and maintain the interest of readers, and to convince them of the merits of the author’s point of view. However, when writing a scientific article, authors must use these ‘persuasive communication devices’ carefully. In particular, they must be explicit about the limitations of their work, avoid obfuscation, and resist the temptation to

Safety and clinical feasibility of injecting a novel liquid fiducial marker for use in image guided radiotherapy in 15 patients with non-small cell lung cancer are reported. No major safety or toxicity issues were encountered. Markers present at start of radiotherapy remained visible in cone beam computed tomography and fluoroscopy images throughout the treatment course and on computed tomography

Goal: Structural brain graphs are conventionally limited to defining nodes as gray matter regions from an atlas, with edges reflecting the density of axonal projections between pairs of nodes. Here we explicitly model the entire set of voxels within a brain mask as nodes of high-resolution, subject-specific graphs. Methods: We define the strength of local voxel-to

This thesis approaches how International Human Rights Law is addressing the protection of indigenous peoples’ right to land when States give concessions for companies to act inside indigenous traditional territory. Cases of harmful conducts committed by companies in indigenous territory are continuously happening around the world. Regional systems of human rights protection, through their state-ce

Annual Report 2013 Æ N I L O R A C Æ N I L O R A C V MR Q T V V E D A Department of Geology Annual Report 2013 LUND UNIVERSITY Table of Contents Prefect’s Letter Research Highlights Continental Dynamics Evolution of the Biosphere Environmental Dynamics Palaeoecology and Palaeoclimatology Biogeochemical Cycles Applied Geology Glacial Geology Solar and Geomagnetic Dynamics 1 3 6 10 12 15 17 19 22 1

https://www.geology.lu.se/sites/geology.lu.se/files/annual_report_2013.pdf - 2026-05-22

Regional Specification of Neurosphere Cultures Derived from Subregions of the Embryonic Telencephalon Regional Specification of Neurosphere Cultures Derived from Subregions of the Embryonic Telencephalon M alin P arm ar,1 C harlotta S kogh, And ers Björklund , and K enneth C a m p b ell2 Wallenberg Neuroscience Center, Division of Neurobiology, Lund University, Solvegatan 17, BMC A11, S-221 84 Lu

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_molecular_and_cellular_neuroscience.pdf - 2026-05-22

ajcn108159 345..352 Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: results from the TEDDY study1,2 Andreas Beyerlein,3* Xiang Liu,4 Ulla M Uusitalo,4 Minna Harsunen,3 Jill M Norris,5 Kristina Foterek,6 Suvi M Virtanen,7–10 Marian J Rewers,5 Jin-Xiong She,11 Olli Simell,12 Ake Lernmark,13 William Hagopian,14 Beena Akolkar,15 Anette-G Ziegler,3 Jeffrey P Krischer,4 San

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_48_beyerlein_ajcn_2015.pdf - 2026-05-22

Background: The Abdominal Compartment Society (WSACS) established consensus definitions and recommendations for the management of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) in 2006, and they were last updated in 2013. The WSACS conducted an international survey between 2022 and 2023 to seek the agreement of healthcare practitioners (HCPs) worldwide on current and n

BACKGROUND: Treatment of newly diagnosed advanced-stage ovarian cancer typically involves cytoreductive surgery and systemic chemotherapy. We conducted a trial to investigate whether the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery would improve outcomes among patients who were receiving neoadjuvant chemotherapy for stage III epithelial ovarian ca

Stellar mergers and accretion events have been crucial in shaping the evolution of the Milky Way (MW). These events have been dynamically identified and chemically characterized using red giants and main-sequence stars. RR Lyrae (RRL) variables can play a crucial role in tracing the early formation of the MW since they are ubiquitous, old (t ≥ 10 Gyr) low-mass stars and accurate distance indicator