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Methods: Three hundred and eighty newly diagnosed ANCA-associated vasculitis patients from six European multicentre studies treated with AZA maintenance were included; 58% were male, median age at diagnosis 59.4 years (interquartile range: 48.3-68.2 years); granulomatosis with polyangiitis, n = 236; microscopic polyangiitis, n = 132; or renal limited vasculitis, n = 12. Patients were grouped accor
Background: The calcipotriol/betamethasone dipropionate two-compound product is safe and effective in the short-term treatment of psoriasis. Objective: The primary objective was to investigate the safety of two treatment regimens involving use of the two-compound product over 52 weeks. The efficacy results are presented here. Methods: Six hundred and thirty-four patients were randomised double-bli
The aim of this study was to optimize the use of BMD measurements in case finding strategies. The use of clinical risk factors with and without BMD was explored in a random sample of the Sheffield female population greater than or equal to75 years of age. The use of clinical risk factors alone could identify women well above or well below a threshold of fracture risk. BMD assessment can be confine
We report on an experimental and theoretical investigation of x-ray absorption and resonant Auger electron spectra of gas phase O(2) recorded in the vicinity of the O 1s-->sigma(*) excitation region. Our investigation shows that core excitation takes place in a region with multiple crossings of potential energy curves of the excited states. We find a complete breakdown of the diabatic picture for
Objective: Fasting insulin concentrations are often used as a surrogate measure or insulin resistance. We investigated the relative contributions Of fasting insulin and insulin resistance to cardiometabolic risk and preclinical atherosclerosis. Design and methods: The Relationship between Insulin Sensitivity and Cardiovascular disease (RISC) cohort consists of 1326 European non-diabetic. overall h
The angular-momentum induced transition from a deformed state of collective rotation to a noncollective configuration has been studied. In Er-157 this transition manifests itself as favored band termination near I=45 (h) over bar. The feeding of these band terminating states has been investigated for the first time using the Gammasphere spectrometer. Many weakly populated states lying at high exci
Omsättningen av kisel (Si) är en av de viktiga biogeokemiska processerna på jorden. Den lösta formen av Si (DSi) är ett nödvändigt näringsämne för såväl markens som havens ekosystem. Löst kisel kommer från den långsamma kemiska vittringen av kiselmineral. Denna process förbrukar koldioxid och bidrar därför till att reglera jordens klimat genom årmiljonerna. Kisel transporteras huvudsakligen via oSilicon (Si) cycle is one of Earth's major biogeochemical cycles. Furthermore, the dissolved form of Si (DSi) is an essential nutrient for both terrestrial and marine ecosystems. DSi ultimately derives from the slow process of chemical weathering of silicate minerals, a mechanism that consumes carbon dioxide, and therefore participates in regulating Earth's climate over geologic timescales. Si is
We have studied the nature of the S 2p → 4eg shape resonance in the SF6 molecule by performing two different experiments. Soft X-ray emission spectra measured at the 4eg shape resonance reveal features that do not originate from the S 2p-1 states. One of the features can be assigned to the 6a1g → S 2p transition. The 6a1g orbital, which is empty in the molecular ground state, can be populated eith
High latitude peatlands play a significant role in global soil carbon budgets, attributed to the slow decomposition rate of Sphagnum mosses that facilitates carbon sequestration through the build-up of peat. As climate change is predicted to increase soil temperatures and decomposition rates of organic matter, studying environmental and intraspecific mechanisms that controls decay resistance of Sp
The emphasis here is the need to understand both the normative gap and the role of digital architecture in order to display the inherent challenge that copyright meets in a digital society. Consequently, in being a descriptively focused study, this article studies contemporary Hungarian copyright and contrasts this to the findings from a survey with over 500 respondents from the Hungarian file-sha
Popular Abstract in Swedish I gruppen huvudhalscancer ingår tumörer i övre luftvägar och svalg. Riskfaktorer för huvudhalscancer är rökning och alkoholöverkonsumtion. Under de senaste 20-30 åren har det skett en påtaglig ökning av insjuknandet, 4-5% per år, i det som kallas orofaryngeal cancer. Orofaryngeal cancer utgår från mellansvalget; mandlar, tungbas och mjuka gommen. Ökningen sammanfaller mThe treatment for head and neck squamous cell carcinoma (HNSCC) is surgery or (chemo)radiotherapy +/- surgery. Side effects related to therapy are long lasting and adversely affects quality of life. The incidence of oropharyngeal cancer is increasing and patients commonly present an advanced tumour stage with neck metastases at the time of diagnosis. The treatment protocol previously comprised rad
We present spectral hole-burning measurements on the 879 nm, I-4(9/2) -> F-4(3/2) transition in Nd3+ : YVO4. We observe antiholes in the spectrum along with long lived spectral holes, which demonstrates optical pumping between the ground state Zeeman levels. The spectral holes are narrow (homogeneous linewidth of 63 kHz) at 2.1 K with a 300 mT applied magnetic field. We also perform preliminary sp
Objective Guidelines on histopathological techniques and reporting for adult and paediatric gastrointestinal neuromuscular pathology have been produced recently by an international working group (IWG). These addressed the important but relatively neglected areas of histopathological practice of the general pathologist, including suction rectal biopsy and full-thickness intestinal tissue. Recommend
We explored impacts of climate change on the geographic distribution of European beech by applying state of the art statistical and process-based models, and assessed possible climate change impacts on both adaptive capacity in the centre of its distribution and adaptive responses of functional traits at the leading and trailing edge of the current distribution. The species area models agree that
Plasmon modes of the exact same individual gold nanoprisms are investigated through combined nanometer-resolved electron energy-loss spectroscopy (EELS) and cathodoluminescence (CL) measurements. We show that CL only probes the radiative modes, in contrast to EELS, which additionally reveals dark modes. The combination of both techniques on the same particles thus provides complementary informatio
Global climate change is characterized by increasing and differentiated exposure to climate-related hazards such as floods, landslides, avalanches, storms, and wildfires (IPCC 2018, 2022). There is a significant volume of research on the effects of such events, and over the last decade, much of this research has been directed at where most lives and values can be saved by protective measures (e.g.
This study explores a novel approach to utilizing waste biomass for syngas production, with the potential for carbon sequestration. An integrated biomass conversion process combining pyrolysis, CO2 reforming, and MILD combustion is proposed. In the proposed system, the bio-oil obtained from pyrolysis can be used in a reforming step, converting it into syngas with a suitable H2/CO ratio for chemica
Natural history museum collections (NHC) represent an underutilized yet valuable resource for tracking environmental changes and anthropogenic impacts on marine ecosystems. Historical samples, particularly foraminifera collected during marine expeditions from the late 1800s to mid-1900s, offer crucial baseline data pre-dating significant human influence. These collections, often accompanied by oce
Uppsatsen behandlar de konflikter om skogen i Böda kronopark på norra Öland som utspelade sig mellan staten och den lokala allmogen under perioden ca 1835-1850. Bakgrunden är den nya skogspolitik som statsmakterna börjar praktisera under första halvan av 1800-talet, där skogen ses som ett kapital som ska förmeras genom långsiktiga och på skogsvetenskaplig grund upplagda planer. I samband härmed om
