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Introduction: No national recommendation for antibiotic prophylaxis for planned caesarean section in Sweden exists. Swedish delivery units have chosen different strategies. Some units routinely administer antibiotic prophylaxis to all women for whom a caesarean section is planned, while other units give prophylactic antibiotics to risk groups only. We took advantage of this “natural experiment” to
High-Arctic environments are facing an elevated pace of warming and increasing human activities, making them more susceptible to the introduction and spread of alien species. We investigated the role of human disturbance in facilitating the spread of a native plant (Papaver dahlianum) in a high-Arctic natural environment close to Isfjord Radio station and along adjacent hiking trails at Kapp Linné
Background: Long-term data on safety and efficacy of instantaneous wave-free ratio (IFR) vs fractional flow reserve (FFR) in guiding percutaneous coronary intervention (PCI) is lacking. Objectives: This study sought to evaluate the 5-year clinical outcomes of IFR- vs FFR-guided PCI in a real-world setting. Methods: We assessed the 5-year outcomes of all patients undergoing IFR or FFR assessment be
Soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory marker that has been shown to predict poorer outcomes in cardiovascular disease and after cardiac surgery. The relationship between suPAR concentrations and postoperative complications after valvular surgery, however, remains unclear. This study aims to evaluate the predictive value of suPAR concentrations for infection, a
Digitalization is shaping the discipline and practice of marketing. Not only does digitalization shape how we shop and consume everything from music to food and mobility services (Cochoy, Hagberg, McIntyre, & Sörum, 2017; Fuentes, Hagberg, & Kjellberg, 2019; Guyader, 2018; Schneider & Eli, 2022), but it has also fundamentally transformed the practices of marketing. Digitalization has c
Övergången till mer hållbara livsmedelssystem och växtbaserade proteinkällor har blivit allt viktigare för att minska livsmedelssystemets klimatpåverkan. Rapsfrökaka är en restprodukt från oljeextraktion med potential att användas som råvara för proteinutvinning och vidare tillämpning i växtbaserade livsmedel tack vare dess balanserade komposition av aminosyror. På grund av bitter smak och högt inThe transition to more sustainable food systems and plant-based protein sources has become increasingly important in reducing the climate impact of the food system. Rapeseed press cake is a by-product of oil extraction that has the potential to be used as a raw material for protein extraction and further use in plant-based foods, thanks to its balanced amino acid profile. Due to its bitter taste a
Patient-specific fluid-structure interaction (FSI) simulations can improve the understanding of mitral valve dysfunction and support preoperative planning. However, existing contracting left ventricular (LV) FSI models are often computationally demanding which limits their clinical applicability. This thesis addresses these limitations by developing a patient-specific contracting LV model within a
ObjectiveTo compare the early and midterm outcomes of left subclavian artery revascularization during thoracic endovascular aortic repair (TEVAR) following carotid subclavian bypass/transposition (CSB) vs. fenestrated repair when landing in zone 1/2. Propensity score matching (PSM) was applied to adjust for baseline differences.MethodsDEbranching versus FENestrated Repair for Left SubClavian Arter
This study examines landslide occurrence and post‑landslide recovery dynamics in Nyungwe Forest Reserve, Rwanda, using a combination of multi‑temporal landslide mapping, environmental and geomorphological predictor analysis, and an assessment of the Tropical Moist Forest (TMF) product. A landslide inventory covering the period from 2000 to 2024 was produced using high‑resolution optical imagery. T
Objective This study attempted to quantify the bias expected due to partly interval-censored (IC) outcomes in the estimated association between hydroxychloroquine (HCQ) taper/cessation and time to disease flare among individuals with systemic lupus erythematosus (SLE). Methods Using data-driven simulations, we estimated bias expected due to IC using real-world data from the Systemic Lupus Internat
Fractures pose a significant burden on society, making prevention strategies important. One approach is to increase physical activity (PA), which may enhance bone mass and muscle strength, thereby lowering fracture risk. A total of 3476 children who began 1st grade (mean age 7 years) between 1998 and 2012 in four Swedish schools were included. The intervention group was 1328 children from one scho
pnas201303829 1..6 Generation of induced neurons via direct conversion in vivo Olof Torpera,b, Ulrich Pfisterera,b,1, Daniel A. Wolfa,b,1, Maria Pereiraa,b, Shong Laua,b, Johan Jakobssona,b, Anders Björklunda,2, Shane Grealisha,b, and Malin Parmara,b,2 aDepartment of Experimental Medical Science, Wallenberg Neuroscience Center, and bLund Stem Cell Center, Lund University, 221 84 Lund, Sweden Contr
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/torper.pdf - 2026-07-06
OBJECTIVES: Patients with chronic obstructive pulmonary disease (COPD) who also have acute coronary syndromes are a high-risk population with a high mortality rate. Little is known about these patients following coronary artery bypass grafting (CABG). METHODS: Patients presenting with acute coronary syndromes between 2006 and 2014 with an angiogram showing 3-vessel disease or left main coronary ar
A comparison was made between two plant peroxidases, cationic horseradish peroxidase (HRP) and anionic tobacco peroxidase (TOP), combined with a highly cationic osmium polymer [Os(4,4'-dimethyl-2,2'-bipyridine)2poly(N-vinylimidazole)10Cl]+2/+ ([Os(dmp)PVI]+/2+) to develop highly sensitive, stable and selective hydrogen peroxide biosensors. The two different plant peroxidases were individually immo
Osteoporosis is a common disease with a strong genetic component, characterized by reduced bone mineral density and increased fracture risk. Although the genetic basis of osteoporosis is incompletely understood, previous studies have identified a polymorphism affecting an Sp1 binding site in the COLIA1 gene that predicts bone mineral density and osteoporotic fractures in several populations. Here
UNLABELLED: The VDR is a candidate gene for osteoporosis. Here we studied five common polymorphisms of VDR in relation to calcium intake and vitamin D status in a population-based cohort of 3100 British women, but found no significant association with bone mass, bone loss, or fracture.INTRODUCTION: Population studies of vitamin D receptor (VDR) polymorphisms have produced conflicting results. We p
Den yttersta barriären mellan luften och blodomloppet i våra lungor består av en lipid-protein film. Denna lipid-protein blandning kallas för lungsurfaktant. Filmen bestående av lungsurfaktant stabiliserar alveolerna i våra lungor och gör att vi kan andas utan motstånd. Brist av lungsurfaktant kan orsaka svåra sjukdomar, till exempel hos förtidigt födda barn som ännu inte hunnit bilda tillräckligtThis thesis explores lipid self-assembly and aims to give a broad picture of self-assembly structures in simple and complex lipid-protein systems. The systems studied are lung surfactant, stratum corneum and simple model membranes. The lung surfactant mixture lines the alveolus in our lungs and stabilises the air- tissue interface. The lung surfactant lipid phase behaviour was here investigated wi
Fire frequency is changing globally and is projected to affect the global carbon cycle and climate. However, uncertainty about how ecosystems respond to decadal changes in fire frequency makes it difficult to predict the effects of altered fire regimes on the carbon cycle; for instance, we do not fully understand the long-term effects of fire on soil carbon and nutrient storage, or whether fire-dr
BACKGROUND: Epidemiological evidence on the association between ambient air pollution and breast cancer risk is inconsistent. OBJECTIVE: We examined the association between long-term exposure to ambient air pollution and incidence of postmenopausal breast cancer in European women. METHODS: In 15 cohorts from nine European countries, individual estimates of air pollution levels at the residence wer
