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Here we present a toolbox for natural language processing tasks related to SARS-CoV-2. It comprises English dictionaries of synonyms for SARS-CoV-2 and COVID-19, a silver standard corpus generated with the dictionaries and a gold standard corpus of 10 Pubmed abstracts manually annotated for disease, virus, symptom and protein/gene terms. This toolbox is freely available on github and can be used f

BACKGROUND: We investigated the causality of IL-8 on carotid intima-media thickness (c-IMT), a measure of sub-clinical atherosclerosis.METHODS: The IMPROVE is a multicenter European study (n = 3,711). The association of plasma IL-8 with c-IMT (mm) was estimated by quantile regression. Genotyping was performed using the Illumina CardioMetabo and Immuno chips. Replication was attempted in three inde

Cutting edge preparation is crucial in metal cutting as the edge geometry significantly influences both the material removal process and tool life. However, an analytical model that can physically describe the cutting edge preparation process has not yet been established. Taking the wet abrasive jet machining (WAJM) method as an example, the following questions always remain: Why does WAJM always

As artificial intelligence continues to evolve, neuromorphic technologies, which emulate biological neural networks, are increasingly seen as a promising direction. Two-dimensional materials are considered promising for neuromorphic applications due to their tunable electrical and optoelectronic properties. In this work, a back-gated tin disulfide (SnS2) field-effect transistor (FET) is electrical

Age-Friendly Cities and Communities (AFCC) is a key global WHO initiative aimed at fostering environments that promote healthy aging for everyone. As AFCC initiatives continue to expand, there is an increasing need to enhance monitoring and evaluation systems to effectively assess their progress and impact. However, significant knowledge gaps persist, particularly in the development of evaluation

Staphylococcus aureus remains one of the most elusive targets in bacterial vaccinology, primarily due to its complex immune evasion strategies and the phenomenon of immune imprinting. Despite decades of research and numerous clinical trials, no vaccine has demonstrated protective efficacy in humans. This review examines the underlying reasons for these failures and proposes a rational, integrativ

The role of anyonic statistics stands as a cornerstone in the landscape of topological quantum techniques. While recent years have brought forth encouraging and persuasive strides in detecting anyons, a significant facet remains unexplored, especially in view of connecting anyonic physics to quantum information platforms—whether and how entanglement can be generated by anyonic braiding. Here, we d

IntroductionThe evidence for assessing whether a single stab injury to the trunk was inflicted by another person in an assault or self-inflicted has primarily been derived from autopsy studies. In this study, we investigate whether victim demographics, crime scene circumstances, and the injury characteristics of assault survivals are interchangeable with homicide characteristics, with a specific f

This thesis aims to investigate the novel physics around Majorana bound states (MBSs). MBSs are quasiparticle excitations predicted to exist in topological superconductors. Due to the inherent protection they obtain from their topology, they have long been regarded as a promising setup to build a topologically protected quantum computer. Apart from this very practical application, they continue to

The Majorana tetron is a prototypical topological qubit stemming from the ground-state degeneracy of a superconducting island hosting four Majorana modes. This degeneracy manifests as an effective nonlocal spin degree of freedom, the most paradigmatic signature of which is the topological Kondo effect. Degeneracies of states with different fermionic parities also characterize minimal Kitaev chains

Cell type annotation remains a critical bottleneck, with current methods often inaccurate and requiring extensive manual validation, particularly in disease contexts. While large language models (LLMs) show promise, they can be unreliable due to hallucinations. We developed CyteType, a multi-agent framework that generates competing hypotheses grounded in full expression data and study context, val

The BCR::ABL1 tyrosine kinase inhibitors (TKIs) in CML represent a paradigm for molecularly targeted therapy. However, clinical outcomes - rate/depth of response, treatment-free remission (TFR), progression to blast crisis (BC) - and adverse events vary among patients. While additional somatic mutations have been invoked to explain varying clinical outcomes, we here propose a complementary perspec

Aims: Individuals with type 1 diabetes (T1D) are typically diagnosed at a young age and exposed to lifelong hyperglycaemia. Despite improved metabolic control, the risk of vascular complications remains challenging. However, some individuals remain free from developing major diabetic complications even after long duration, so-called “escapers”. This study investigated transcriptomic biomarkers lin

This study presents the fabrication of all-dielectric silicon-based twisted L-shape metamaterials using a two-step electron-beam glancing angle deposition approach. Systematic chiroptical characterization and optimization are performed through Mueller matrix generalized spectroscopic ellipsometry and finite element modeling, demonstrating tunable, broadband chirality response with potential applic

Tuning the spectral and directional characteristics of thermal emission is critical for advancing technologies such as thermophotovoltaics (TPVs), passive thermal radiative cooling (PTRC), and solar thermophotovoltaics (STPVs), yet scalable fabrication methods remain limited. Here, femtosecond laser surface processing (FLSP), a top-down ablation and re-solidification approach is employed, to creat

Speaking in poor acoustic conditions constitutes a risk factor for voice disorders. This study investigated how speaker’s comfort and vocal effort were affected during short speech tasks in four different room acoustic configurations. Voice recordings of the speech tasks and self-evaluations of the speaker’s comfort were collected from 15 participants in four room acoustic configurations as part o

Cardiovascular disease (CVD) is the leading cause of death in Europe, with myocardial infarction (MI) being one of its most severe manifestations. While many risk factors for CVD are well known, occupational exposures remain relatively understudied—especially in analyses that adjust for co-occurring workplace exposures. This study aimed to examine the association between occupational exposure to c

Peripheral nerve tumours, most commonly schwannomas and neurofibromas, might present significant challenges by eliciting physical symptoms and emotional distress. We aimed to explore patients’ expectations, perceptions, and experiences regarding their diagnosis and the surgical treatment of a nerve tumour in the upper limb. Fourteen adults (10 women, 4 men; age range 35–85) from two Swedish hand s