Filtyp
The signal crayfish (Pacifastacus leniusculus) was introduced to Sweden in 1960, and it has a high commercial and recreational value, but it may also have negative effects on native ecosystems. To better predict how climate warming will affect population dynamics of this cool-water crayfish, we explored the role of temperature and density dependence as explanatory factors of the subsequent years’
A research-based understanding of permafrost distribution at a sufficient spatial resolution is important to meet the demands of science, education and society. We present a new permafrost map for Norway, Sweden and Finland that provides a more detailed and updated description of permafrost distribution in this area than previously available. We implemented the CryoGRID1 model at 1km2 resolution,
Background Abiraterone acetate (AA) prolongs survival in metastatic castration-resistant prostate cancer (mCRPC) patients. To measure treatment response accurately in bone, quantitative methods are needed. The Bone Scan Index (BSI), a prognostic imaging biomarker, reflects the tumour burden in bone as a percentage of the total skeletal mass calculated from bone scintigraphy. Objective To evaluate
In continental margin basins, the hydrogeological setting is complex due to transgression/regression events that removed old sediments in the basin and formed new geologic units. Due to the geological complexity, the use of vertical electrical sounding has proven to be insufficient for groundwater explorations. The lack of understanding the geological underground has resulted in many boreholes wit
Background: The International Society for Heart and Lung Transplantation (ISHLT) guidelines advise against inappropriate weight match (IWM) for heart transplant, defined as donor weight <70% of recipient's weight. Few studies have explored in detail this size-matching recommendation, especially with regard to body mass index (BMI) and gender matching. We aimed to determine whether any difference c
Objective: This study aims to illuminate expectant first-time fathers’ experiences of participation during pregnancy in three Nordic countries. Background: Fathers’ participation in pregnancy is associated with improved health for the family as a whole. Research so far has primarily explored fathers’ participation in pregnancy within health care settings. It is important to know more about how fa
In the present work, the antimicrobial activity of different pressurized liquid extracts obtained from Haematococcus pluvialis microalga was tested against several microorganisms of importance for the food industry (Escherichia coli, Staphylococcus aureus, Candida albicans and Aspergillus niger). Extractions were performed with hexane and ethanol at four different temperatures (50, 100, 150 and 20
In this work, a new copolymer synthesized in our laboratory is used as physically adsorbed coating for capillary electrophoresis (CE). The copolymer is composed of ethylpyrrolidine methacrylate (EPyM) and methylmethacrylate (MMA). The capillary coating is easily obtained by simply flushing into the tubing an EPyM/MMA solution. It is demonstrated that the composition of the EPyM/MMA copolymer toget
Aims: The aim of the study was to compare outcomes in unfractionated heparin (UFH) and bivalirudin-treated patients undergoing primary percutaneous coronary intervention (PPCI). Methods and results: This observational study contained 20,612 PPCI patients treated with either UFH monotherapy or bivalirudin with or without concomitant UFH. Patients with oral anticoagulant or glycoprotein IIb/IIIa inh
PURPOSE: Increased joint laxity has been associated with the risk of ligament injury and development of osteoarthritis in large joints such as the knee, but this has not been investigated in depth in the hand. We hypothesized that generalized joint laxity would correlate with radiographic measures of trapeziometacarpal (TM) joint subluxation, as measured in carpometacarpal stress view radiographs.
Background: Pain is a frequent symptom of idiopathic Parkinson’s disease and has a substantial impact on quality of life. The King’s Parkinson’s disease pain scale (KPPS) has become internationally established and is an English-language, standardized, reliable and valid scale for evaluation of pain in idiopathic Parkinson’s disease. This article presents a validated version in German. Method: The
The design of an in vitro immunization system based on a synthetic heterotope immunogen, which was a peptide containing both T- and B-cell epitopes, that elicited a neutralizing, primary human humoral immune response against the human immunodeficiency virus (HIV-1) is reported here. This heterotope construct contained the major neutralizing B-cell epitope, within the V3 region of glycoprotein 120
Anaerobic co-digestion is an emerging practice at wastewater treatment plants (WWTPs) to improve the energy balance and integrate waste management. Modelling of co-digestion in a plant-wide WWTP model is a powerful tool to assess the impact of co-substrate selection and dose strategy on digester performance and plant-wide effects. A feasible procedure to characterise and fractionate co-substrates
The rapid advances in life science, including the sequencing of the human genome and numerous other techiques, has given an extraordinary ability to aquire data on biological systems and human disease. Even so, drug development costs are higher than ever, while the rate of new approved treatments is historically low. A potential explanation to this discrepancy might be the difficulty of understand
Purpose – Scenarios have become a vital methodological approach in business as well as in public policy. When scenarios are used to guide analysis and decision-making, the aim is typically robustness and in this context we argue that two main problems at scenario set level is conservatism, i.e. all scenarios are close to a perceived business-as-usual trajectory and lack of balance in the sense of
The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. At low concentrations of denaturant the transition state occurs early in the folding reaction, whereas at high denaturant concentration it moves close to the nati
Popular Abstract in Swedish Avhandlingen är en studie av kvinnors brevskrivning i Sverige under 1700-talet. Breven är skrivna av ett antal kvinnor från de högre samhällsskikten (adel och borgerskap) under 1780- och 1790-talen. Flertalet av breven är skrivna på svenska, men några också på franska. Huvudsyftet med avhandlingen är att undersöka relationen mellan idén om att kvinnor skrev annorlunda, This dissertation is a study of women's letter-writing in eighteenth-century Sweden. The letters are written by a number of women from the uppper classes (nobility and bourgeoisie) during the last two decades of the eighteenth century. The majority of the letters are written in Swedish, some however in French. The main aim is to examine the relationship between the idea of women as a special kind
The field of phylogenomics has emerged during the last five years, as the number of fully or partially sequenced genomes has increased rapidly. Using whole genomes for phylogenetic studies greatly increases the accuracy of the trees determined, and can potentially resolve phylogenetic questions that could not be resolved bu studies using only a few gene sequences. In the current thesis selected
Purpose: To investigate the change in incidence of referred carpal tunnel syndrome (CTS) and carpal tunnel release (CTR) surgery over time and regional variations. Methods: From the nationwide patient registry, we identified all adult individuals who had received first-time CTS diagnosis (International Classification of Diseases, 10th Revision code G560) at secondary or tertiary level and first-ti
A tropical maritime case of deep convective clouds was studied using a state-of-the-art aerosol-cloud model in order to evaluate the microphysical mechanisms of aerosol indirect effects (AIE). The aerosol-cloud scheme used is a hybrid bin/bulk model, which treats all phases of clouds and precipitation allowing a detailed analysis of process
