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Cerebro-spinal fluid biomarker levels : phosphorylated tau (T) and total tau (N) as markers for rate of progression in Alzheimer's disease

BACKGROUND: We investigated the potential associations between cerebro-spinal fluid (CSF) levels of phosphorylated tau (P-tau) and total tau (T-tau) with short-term response to cholinesterase inhibitor (ChEI) treatment, longitudinal outcome and progression rates in Alzheimer's disease (AD). METHODS: This prospective, observational study included 129 participants clinically diagnosed with mild-to-m

The influence of women's fear, attitudes and beliefs of childbirth on mode and experience of birth

Background: Women's fears and attitudes to childbirth may influence the maternity care they receive and the outcomes of birth. This study aimed to develop profiles of women according to their attitudes regarding birth and their levels of childbirth related fear. The association of these profiles with mode and outcomes of birth was explored.Methods: Prospective longitudinal cohort design with self

Acute heart failure: causes and outcomes by stages of chronic kidney disease and heartfailure phenotypes

Purpose: To investigate the relationship between heart failure (HF) and chronic kidney disease (CKD) by analysing the prevalence of different stages of CKD and other morbidities in patients admitted with acute heart failure (AHF), as well as readmissions and mortality.Introduction: Chronic kidney disease (CKD) is more prevalent among all phenotypes of HF patients than in the general population. It

Final persian 190911

FINAL Persian 190911.pdf GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Persian Language Courses 
 Version 1.0, August 2019 For an always up-to-date online version, please visit the course site (check regularly for updates) Welcome! Welcome to the Autumn term’s courses in Persian Graduate School offers courses in modern Persian, which are open to all Graduate School students. The cou

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/final_persian_190911.pdf - 2026-06-01

12. optimering

Optimering Optimering av dosplanering Crister Ceberg Optimering av dosplanering • Introduktion • Dosplanering • Matematisk formulering – Optimeringsvariabeln – Målfunktionen – Begränsningar • Lösningsmetoder • Realisering • Optimering av multipla kriterier Introduktion • Historia I – Lat. optimum = ”det ultimata idealet” – Studerats sedan antiken (av bla Arkimedes, Euklides, Heron) – Ett klassiskt

https://www.msf.lu.se/sites/msf.lu.se/files/12._optimering.pdf - 2026-06-01

High- and Low-Fat Dairy Consumption and Long-Term Risk of Dementia : Evidence From a 25-Year Prospective Cohort Study

BACKGROUND AND OBJECTIVES: The association between dairy intake and dementia risk remains uncertain, especially for dairy products with varying fat contents. The aim of this study was to investigate the association between high-fat and low-fat dairy intake and dementia risk.METHODS: This study used data from a prospective cohort in Sweden, the Malmö Diet and Cancer cohort, which consisted of commu

Gadodiamide injection for Enhancement of MRI in the CNS. Applications, dose, field and time dependence.

Popular Abstract in Swedish Magnetresonanstomografi (MRT) är en metod för framställning av bilder av kroppen och av sjukliga förändringar i kroppen. När metoden introducerades ansågs den utomordentligt goda inbyggda vävnadskontrasten vara tillräcklig för att särskilja olika sjukliga förändringar, speciellt i hjärnan. Det har emellertid visat sig att förmågan att upptäcka sjukliga förändringar är oAims of the study The aims of this study using Gadodiamide injection were to investigate: · Whether Gadodiamide injection was comparable to Gd-DTPA for the enhancement of CNS lesions. · The contrast effect at different field strengths. · The effective time-window for the enhancement of blood-brain barrier damage. · The relations between the concentration of contrast agent and enhancement in p

Hereditary risk factors for stroke in humans - Association studies with emphasis on familial and genotypic factors

Popular Abstract in Swedish Stroke, eller slaganfall, är en sammanfattande benämning på sjukdomar som drabbar blodförsörjningen i hjärnan. Varje år insjuknar cirka 30000 personer i Sverige i stroke, av dessa drabbas cirka 15% av blödningar medan resterande 85% får infarkter, dvs blodpropp i hjärnan. Stroke upptar fler vårddagar i slutenvården än någon annan somatisk sjukdom. Medianåldern för insjuBackground Stroke is a serious vascular disorder that comprises intracerebral hemorrhages, subarachnoid hemorrhages and ischemic stroke (IS). The etiology of stroke, including hereditary components induced by cellular mechanisms, is therefore a research field of vital importance. The aim of this thesis was to assess possible genetic impact on stroke risk. We thus evaluated family history of strok

Helicobacter pylori infection in a mouse model: Development, optimization and inhibitory effects of antioxidants

Popular Abstract in Swedish Helicobacter pylori är en spiralformad Gramnegativ human-specifik patogen, som kan penetrera magsäckens slemlager och kolonisera epitelskiktet. H. pylori infektion är en högriskfaktor för utvecklandet av kronisk gastrit, magsår och ventrikelcancer. Både aktivt växande spiralformer av H. pylori och dess runda viloformer framkallar kronisk magkatarr (gastrit) i BALB/cA möHelicobacter pylori is a human pathogen strongly associated with chronic type B gastritis, peptic ulcer disease, gastric cancer and MALT lymphoma. Our aims were to establish a mouse model of H. pylori infection, to study pathogenesis of gastritis and gastric cancer and to investigate new treatment strategies in this model. Both spiral and coccoid forms of H. pylori strains 17874, 25 and 553/93 cau

Are affordable pharmaceuticals within reach for developing countries - Clarifying the access situation of today and projecting beyond the Paragraph 6-Agreement

The increasing spread of global pandemics such as HIV/AIDS, tuberculosis (TB) and malaria, in particular in developing countries, has forced the engagement of industrialized countries and pharmaceutical companies. Because medicines to cure these diseases are often under patent protection, they are not affordable for people in developing countries where health crises prevail. In November 2001, WTO

The cardiorenal syndrome: Structural and functional aspects including associations with the shrunken pore syndrome

Mild to moderate renal impairment affects 10% of the general population. Renal impairment is difficult to detect because of the lack of symptoms, but it can be estimated by calculating the estimated glomerular filtration rate (eGFR) on the basis of plasma creatinine and/or cystatin C concentrations. Chronic kidney disease (CKD) is associated with an increased risk of development of cardiovascular

Effectiveness of smartphone-based community case management on the urgent referral, reconsultation, and hospitalization of children aged under 5 years in malawi : Cluster-randomized, stepped-wedge trial

Background: Integrated community case management (CCM) has led to reductions in child mortality in Malawi resulting from illnesses such as malaria, pneumonia, and diarrhea. However, adherence to CCM guidelines is often poor, potentially leading to inappropriate clinical decisions and poor outcomes. We determined the impact of an e-CCM app on the referral, reconsultation, and hospitalization rates

Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302) : final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study

BACKGROUND: Abiraterone acetate plus prednisone significantly improved radiographic progression-free survival compared with placebo plus prednisone in men with chemotherapy-naive castration-resistant prostate cancer at the interim analyses of the COU-AA-302 trial. Here, we present the prespecified final analysis of the trial, assessing the effect of abiraterone acetate plus prednisone on overall s

No title

Popular Abstract in Swedish Syftet med den här studien är att undersöka utvecklingen av språkfärdigheten i skriftlig produktion av franska som främmande språk. Vi har följt 5 inlärares produktion av franska i en 30 månader lång longitudinell studie. För att kunna utvärdera färdigheten har vi använt oss av parametrarna flyt, komplexitet och korrekthet. Flyt och komplexitet har utvärderats med hjälpThe aim of this study is to examine the development of linguistic proficiency in written production of second-language French. In a longitudinal study of 30 months, we follow the written production of 5 guided learners of French as a second language. In order to apprehend proficiency we use the conventional parameters fluency, complexity and accuracy. The fluency and complexity are apprehended by

Using surveillance cameras to analyze the activity pattern of the Eurasian otters (Lutra lutra) and the efficiency of camera trap monitoring

Aim: The Eurasian otter (Lutra lutra) is a flagship species for global freshwater ecosystems. As one of the most widely distributed Palearctic mammals, the otter used to inhabit most provinces in China. However, after decades of relentless hunting and habitat degradation, the Sanjiangyuan Region is now one of last strongholds for this species in China. Currently, there still remains an enormous kn

Resection of colorectal liver metastases - Impact of preoperative chemotherapy

Background Colorectal cancer is a leading cause of cancer related death worldwide. 20-30 % of patients will develop colorectal liver metastases (CRLMs). Surgical resection is the mainstay of treatment for CRLMs, and is often combined with perioperative chemotherapy, which can prolong progression-free survival after resection. Moreover, observation of CRLMs response to preoperative chemotherapy can

JCMS 20th Anniversary Symposium on the Arrival of Normative Power in Planetary Politics

For the past two decades, the ‘Normative Power Approach’ (NPA) has affected both academic and policymaking debates on the European Union (EU) in global politics. Since its publication in the Journal of Common Market Studies in 2002, the Normative Power article has remained one of the highest cited and most influential articles in the study of European integration. Importantly, the NPA is one of th

Longitudinal changes in hippocampal texture from healthy aging to Alzheimer's disease

Early detection of Alzheimer's disease is essential to develop preventive treatment strategies. Detectible change in brain volume emerges relatively late in the pathogenic progression of disease, but microstructural changes caused by early neuropathology may cause subtle changes in the MR signal, quantifiable using texture analysis. Texture analysis quantifies spatial patterns in an image, such as

Shopper Mode- Shopper Marketing from a shopper perspective

Title: Shopper Mode - Shopper marketing from a shopper perspective Date of the Seminar: Lund, 2012-05-30 Course: BUSN29. Master thesis Authors: Charlotte Borgeke Nilsson & Caroline Lundström Ek Advisor: Karin Alm Keywords: Shopper Marketing, shopper perspective, shopper mode, Swedish pharmacy market, Apoteket Hjärtat The thesis purpose: The purpose of this research is to contribute to a greate

Olfaction in Eurasian spruce bark beetle (lps typographus) larvae in response to symbiotic fungi

Sniffing out friends and foes: Bark beetle larvae and fungal scents. A tiny but destructive force is threatening Eurasian forest habitats – the Eurasian spruce bark beetle, Ips typographus. The larvae of this beetle species develop under the bark of conifers and feed on tree tissue. This leads to tree death and thus widespread devastation in wooded landscapes. The beetles live in partnership wit