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Influence of acidosis on lipid peroxidation in brain tissues in vitro

To study the influence of acidosis on free radical formation and lipid peroxidation in brain tissues, homogenates fortified with ferrous ions and, in some experiments, with ascorbic acid were equilibrated with 5–15% O2 at pH values of 7.0, 6.5, 6.0, and 5.0, with subsequent measurements of thiobarbituric acid-reactive (TBAR) material, as well as of water- and lipid-soluble antioxidants (glutathion

Unusual Vesicle-Micelle Transitions in a Salt-Free Catanionic Surfactant: Temperature and Concentration Effects.

The spontaneous formation of vesicles by the salt-free surfactant hexadecyltrimethylammonium octylsulfonate (TASo) and the features of an unusual vesicle-micelle transition are investigated in this work. In a previous work, we have shown that this highly asymmetric catanionic surfactant displays a rare lamellar miscibility gap in the concentrated regime. Here, we analyze in detail the aggregation

Field trials with in-car speed limiter.

Effects of an in-car speed limiter were investigated in three European countries, the Netherlands, Spain and Sweden representing different regions and driving cultures. The study was carried out in urban and surrounding areas. Most of the European speed limit categories, ranging from 30 km/h to 120 km/h were included. The effects of the limiter were greatest in free driving conditions outside plat

BRCA2 gene mutations and coagulation-associated biomarkers

Thromboembolic events are the second cause of death in cancer patients, although the mechanisms underlying this increased thromboembolic risk remain unclear. The aims of this study were to examine whether BRCA2 gene mutations may modify the circulating levels of thrombocoagulation biomarkers and whether breast cancer development may influence changes in such circulating biomarkers. The study was p

Serum choline in extremely preterm infants declines with increasing parenteral nutrition

Purpose: Choline is an essential nutrient for fetal and infant growth and development. Parenteral nutrition used in neonatal care lack free choline but contain small amounts of lipid-bound choline in the form of phosphatidylcholine (PC). Here, we examined the longitudinal development of serum free choline and metabolically related compounds betaine and methionine in extremely preterm infants and h

Characterization of free volume and density gradients of polystyrene surfaces by low-energy positron lifetime measurements

Free volume and density gradient widths of the free surface of high molecular mass polystyrene was characterized by use of a pulsed low-energy positron lifetime beam. A density gradient in terms of mass density (g/cm(3)) versus depth (nm) was obtained from the experimental beam data using a novel approach, yielding a width of the density gradient of approximately 3.5 nm. The procedure accounted fo

Disability pension. Epidemiological and financial aspects.

Popular Abstract in Swedish Avsikten med förtidspensionering är att ge rätt till ekonomisk trygghet om arbetsförmågan skulle reduceras i förtid. Sedan sextiotalet har både totala antalet förtidspensionärer och antalet nybeviljade förtidspensioner ökat kontinuerligt. Efter att 1993 ha kulminerat med över 62.000 nybeviljade pensioner, har antalet därefter minskat. Både för den enskilde och för samhäDuring the last decades, the incidence of disability pension in Sweden has increased continuously and it peaked in 1993 at approximately 62,000 new pensions. Early retirement due to occupational disability often constitutes a problem for the society as well as for the individual. The aim of this thesis was to analyse aspects on the risk of disability pension, to describe changes in health after th

Stability to oxidation of spray-dried fish oil powder microencapsulated using milk ingredients

Microencapsulation of fish oil was achieved by spray-drying homogenized emulsions of fish oil using 3 different types of casein as emulsifier and lactose as filler. As the degree of aggregation of the casein emulsifier increased, the vacuole volume of the microencapsulated powders decreased. The shelf life of the powders increased as the degree of aggregation of the casein emulsifier increased at

Control of excitonic and electron-hole processes in wide-gap crystals by means of elastic uniaxial stress

The time-resolved emission spectra and the excitation spectra of the main emissions have been measured for the first time in stressed and unstressed RbI crystals using synchrotron radiation of 10-30 eV at 8 K. It has been shown that the applied elastic uniaxial stress (EUS) offers promise for the separation of the elementary multiplication mechanisms of electronic excitations. A different influenc

Transient photocurrent of bulk heterojunction solar cell characterized by ns-laser and sub-ms LED

We measure the transient photocurrent of APFO3:PCBM bulk heterojunction solar cells illuminated with ns-laser and sub-ms LED light sources. The ratio of the number of collective charges to the number of excited photon (external quantum efficiency, EQE) and the transient photocurrent fall times have been carried out with difference pulse durations and fluences. The EQEs characterized by ns-laser so

Comparative study on the machinability of lead-free brass

Lead is a heavy metal which is toxic even at low exposure levels. Although the amount of lead used in industry is steadily declining, it still constitutes a common alloying element for most conventional brass varieties. Today, conventional brasses contain roughly 3 wt % lead. One of the main incentives for using lead as an alloying element is that it has a markedly positive effect on the machinabi

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015 : a systematic analysis for the Global Burden of Disease Study 2015

BACKGROUND: Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE a

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015 : a systematic analysis for the Global Burden of Disease Study 2015

BACKGROUND: Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE a

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

Alzheimer's disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder. Despite clinical and experimental evidence implicating the intestinal microbiota in a number of brain disorders, its impact on Alzheimer's disease is not known. To this end we sequenced bacterial 16S rRNA from fecal samples of Aβ precurso

γ-Aminobutyric acid (GABA) production and soluble free amino acid profile change in Andean seeds by Levilactobacillus brevis fermentation

High nutritional value Andean seeds—tarwi (Lupinus mutabilis), cañihua (Chenopodium pallidicaule), and quinoa (Chenopodium quinoa)—were subjected to solid-state fermentation with Levilactobacillus brevis DSM 1269. This strain can convert L-glutamic acid into the neurotransmitter GABA. Fermented tarwi exhibited the highest GABA production, at 4 mg/g sample, which correlates with its higher protein